Evidence map›Paper›PMID 40894836›Full record

ArticleCJC open2025

Characterization of Malnutrition in Atrial Functional Mitral Regurgitation.

Tsukasa Murakami, Nobuyuki Kagiyama, Tomohiro Kaneko, Kazuki Kagami, Masashi Amano, Taiji Okada, Yukio Sato, Yohei Ohno, Kimi Sato, Kojiro Morita and 4 more

Abstract read
In one paragraph

Article in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tsukasa MurakamiDepartment of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Nobuyuki KagiyamaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tomohiro KanekoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazuki KagamiDepartment of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Masashi AmanoDepartment of Heart Failure and Transplantation, National Cerebral and Cardiovascular Center, Suita, Japan.
Taiji OkadaDepartment of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan.
Yukio SatoDepartment of Cardiology, St Marianna University School of Medicine, Kanagawa, Japan.
Yohei OhnoDepartment of Cardiology, Tokai University School of Medicine, Isehara, Japan.
Kimi SatoDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Kojiro MoritaDepartment of Nursing Administration and Advanced Clinical Nursing, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Tomoko Machino-OhtsukaDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Yukio AbeDepartment of Cardiology, Osaka City General Hospital, Osaka, Japan.
Hideki IshiiDepartment of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Masaru ObokataDepartment of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In this study we sought to characterize the prevalence, clinical characteristics, and outcomes of malnutrition in patients with atrial functional mitral regurgitation (AFMR). Methods: This multicentre, observational study included 802 patients diagnosed with AFMR. The Results: At least mild nutrition risk (GNRI ≤ 98) was present in 57% of patients with AFMR. Patients with lower GNRI were older, had lower body mass index, hemoglobin levels, and renal function, and had a higher prevalence of New York Heart Association class III or IV, dementia, and impaired activities of daily living. During the median follow-up duration of 978 (interquartile range, 492-1141) days, 254 primary outcomes were observed. Increasing severity of malnutrition risk categories was associated with higher rates of the primary outcome. Multivariable analysis revealed that a continuous metric of GNRI was associated with the primary outcome after adjusting for multiple confounders (adjusted hazard ratio, 0.76 per 1 standard deviation increment; 95% confidence interval, 0.66-0.87; Conclusions: Patients with AFMR and malnutrition represent a vulnerable population with worse clinical outcomes.

Indexed as

atrial functional mitral regurgitationGeriatric Nutritional Risk Indexheart failuremalnutrition

Identifiers

PMID40894836
PMCPMC12399123

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.