Evidence map›Paper›PMID 40894808›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2025

Investigating Real-World Stability and Sterility of in-Use Insulin-An Urgent Public Health Concern. In Sub-Saharan Africa.

Emmanuel Kimaro, Eveline Thobias Konje, Amani Thomas Mori, Benson Richard Kidenya, Eliangiringa Kaale

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emmanuel KimaroDepartment of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania.ORCID 0000-0003-3123-0477
Eveline Thobias KonjeDepartment of Biostatistics and Epidemiology, School of Public Health, Catholic University of Health and Allied Sciences (CUHAS), Mwanza, Tanzania.
Amani Thomas MoriDepartment of Global Public Health and Primary Care, Section for Ethics and Health Economics, University of Bergen, Bergen, Norway.
Benson Richard KidenyaDepartment of Biochemistry and Molecular Biology, Catholic University of Health and Allied Sciences (CUHAS), School of Medicine, Mwanza, Tanzania.
Eliangiringa KaalePharm R&D Laboratory, School of Pharmacy, Muhimbili University of Health and Allied Sciences (MUHAS), Dar Es Salaam, Tanzania.ORCID 0000-0001-6008-3539

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin stability is a critical yet underexplored factor affecting diabetes outcomes in Sub-Saharan Africa (SSA). High ambient temperatures, unreliable refrigeration, and weak regulatory oversight may compromise insulin quality during storage and use. Patients often rely on traditional, non-validated methods that risk potency loss. This commentary highlights the urgent need for real-world studies on insulin stability and sterility in SSA to inform evidence-based practices and improve glycemic control among diabetic patients in resource-limited settings.

Indexed as

diabetesglycemic controlinsulin stabilityinsulin sterilitySSASub-Saharan Africa

Identifiers

PMID40894808
PMCPMC12390779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.