Evidence map›Paper›PMID 40894683›Full record

ArticlebioRxiv : the preprint server for biology2025

A transcription factor-sRNA-mediated double-negative feedback loop confers pathogen-specific control of quorum-sensing genes.

Ameya A Mashruwala, Kaitlin Decker, Chenyi Fei, Julie Valastayan, Bonnie L Bassler

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ameya A MashruwalaDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Kaitlin DeckerDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Chenyi FeiDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Julie ValastayanDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Bonnie L BasslerDepartment of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.ORCID 0000-0002-0043-746X

Funding

Intra- and Inter- Species Communication in BacteriaR37GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2016 to 2025
$3.4M
NIGMS NIH HHS R37 GM065859
6 · The paper itself

Abstract

The cell-to-cell communication process called quorum sensing enables bacteria to synchronize collective behaviors. Quorum sensing relies on the production, release, and detection of signaling molecules called autoinducers. In

Identifiers

PMID40894683
PMCPMC12393568

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.