Evidence map›Paper›PMID 40894633›Full record

ArticlebioRxiv : the preprint server for biology2025

Conserved Heterochromatin-like Structures with Local Regulators Mediate the Iron Stress Response in Mycobacteria.

Alyssa M Ekdahl, Agata Turula, Jeremy W Schroeder, Rebecca Hurto, Quancheng Liu, Lydia Freddolino, Lydia M Contreras

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alyssa M EkdahlMcketta Department of Chemical Engineering, University of Texas at Austin, Austin TX.ORCID 0000-0003-0683-9336
Agata TurulaMcketta Department of Chemical Engineering, University of Texas at Austin, Austin TX.
Jeremy W SchroederDepartment of Biological Chemistry and Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor MI.ORCID 0000-0001-8829-8494
Rebecca HurtoDepartment of Biological Chemistry and Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor MI.
Quancheng LiuDepartment of Biological Chemistry and Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor MI.ORCID 0009-0004-8207-2629
Lydia FreddolinoDepartment of Biological Chemistry and Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor MI.ORCID 0000-0002-5821-4226
Lydia M ContrerasMcketta Department of Chemical Engineering, University of Texas at Austin, Austin TX.ORCID 0000-0001-5010-5511

Funding

Building a unified framework for understanding bacterial gene regulation and chromosomal architectureR35GM128637 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lydia Petra Freddolino · 2018 to 2026
$3.6M
Novel mechanisms of posttranscriptional regulation by CsrAR01GM135495 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI CONTRERAS, LYDIA MARIA · 2020 to 2024
$1.8M
NIGMS NIH HHS R01 GM135495NIGMS NIH HHS R35 GM128637
6 · The paper itself

Abstract

Recent studies have demonstrated the importance of dynamic heterochromatin-like regions in bacterial gene regulation, particularly for adaptation to changing environments. Here, we have measured the dynamic regulatory protein-DNA landscape of the tuberculosis vaccine strain,

Identifiers

PMID40894633
PMCPMC12393510

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.