Evidence map›Paper›PMID 40894629›Full record

ArticlebioRxiv : the preprint server for biology2025

Drosophila Pyruvate Kinase Links Metabolic State with Circadian Output via TARANIS and PDF.

Sang Hyuk Lee, Oghenerukevwe Akpoghiran, Eunjoo Cho, So Who Kang, Min-Ji Kang, Kyunghee Koh, Eun Young Kim

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sang Hyuk LeeDepartment of Brain Science, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
Oghenerukevwe AkpoghiranDepartment of Neuroscience, the Farber Institute for Neurosciences and Synaptic Biology Center, Thomas Jefferson University, Philadelphia, PA19107, USA.
Eunjoo ChoDepartment of Brain Science, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
So Who KangDepartment of Brain Science, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.ORCID 0000-0001-6611-1991
Min-Ji KangDepartment of Pharmacology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Republic of Korea.
Kyunghee KohDepartment of Neuroscience, the Farber Institute for Neurosciences and Synaptic Biology Center, Thomas Jefferson University, Philadelphia, PA19107, USA.ORCID 0000-0003-0847-8204
Eun Young KimDepartment of Brain Science, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.ORCID 0000-0001-6466-8622

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Molecular and Neural Mechanisms of Sleep Regulation by TARANISR01NS086887 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI KOH, KYUNGHEE · 2015 to 2019
$1.7M
NIH HHS P40 OD018537NINDS NIH HHS R01 NS086887
6 · The paper itself

Abstract

The circadian clock generates ~24-hour rhythms that anticipate daily environmental changes. Circadian clock and glucose metabolism are tightly interconnected, and both are disrupted in aging and disease. To examine how glucose hypometabolism impacts circadian rhythm, we downregulated glycolytic enzymes -

Indexed as

Circadian rhythmglycolysismetabolismPigment dispersing factorTARANIS

Identifiers

PMID40894629
PMCPMC12393403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.