Evidence map›Paper›PMID 40894381›Full record

ArticleRespirology case reports2025

Successful Treatment of Aspergilloma With Antifungal Alone: A Case of Conservative Management.

Ad Rian Chong, Khai Lip Ng, Nai-Chien Huan, Nur Husna Mohd Aminudin, Raja Nor Adilla Raja Rahaizat, Kasuma Mohamed Nordin

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ad Rian ChongDivision of Respiratory Medicine, Department of Internal Medicine Melaka Hospital Melaka Malaysia.ORCID https://orcid.org/0009-0004-1592-9119
Khai Lip NgDivision of Respiratory Medicine, Department of Internal Medicine Melaka Hospital Melaka Malaysia.ORCID https://orcid.org/0000-0002-9868-1398
Nai-Chien HuanDepartment of Respiratory Medicine Queen Elizabeth Hospital Kota Kinabalu Sabah Malaysia.ORCID https://orcid.org/0000-0002-2671-4189
Nur Husna Mohd AminudinDivision of Respiratory Medicine, Department of Internal Medicine Melaka Hospital Melaka Malaysia.
Raja Nor Adilla Raja RahaizatDepartment of Radiology Melaka Hospital Melaka Malaysia.
Kasuma Mohamed NordinDivision of Respiratory Medicine, Department of Internal Medicine Melaka Hospital Melaka Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary aspergilloma can cause life-threatening haemoptysis. Surgical resection and/or bronchial artery embolization (BAE) are established treatment modalities, but both can be risky in frail patients with comorbidities. Spontaneous regression of aspergilloma with antifungal agents alone is rare. We report an elderly gentleman with a background history of treated pulmonary tuberculosis, who presented with haemoptysis due to a large left upper lobe aspergilloma. He declined surgery and BAE due to perceived risks. Oral voriconazole and later isavuconazole were prescribed, which led to clinical improvement and significant reduction in the size of the aspergilloma over 6 months. Antifungal agents might be a viable therapeutic option for aspergilloma patients unsuitable or who declined more invasive procedures. Further studies are needed to validate the efficacy and safety of this approach.

Indexed as

antifungal therapyhaemoptysisisavuconazolenon‐surgical managementpulmonary aspergilloma

Identifiers

PMID40894381
PMCPMC12391585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.