Evidence map›Paper›PMID 40894309›Full record

ArticleCurrent trends in biomedical engineering & biosciences2024

Promising Biomarkers for Spinal Cord Injury: A Brief Review.

Anita Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current trends in biomedical engineering & biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anita SinghAssociate Professor, Bioengineering, Temple University, PA, USA.

Funding

Investigating Injury Tolerance and Mechanisms of Neonatal Brachial Plexus Palsy and Associated InjuriesR01HD104910 · NICHD · WIDENER UNIVERSITY · PI Anita Singh · 2022 to 2026
$2.0M
Biomechanical and Functional Injury Thresholds and Related Histological Changes in Neonatal Brachial PlexusR15HD093024 · NICHD · WIDENER UNIVERSITY · PI SINGH, ANITA · 2017 to 2017
$417k
NICHD NIH HHS R01 HD104910NICHD NIH HHS R15 HD093024
6 · The paper itself

Abstract

Mechanical trauma to the spinal cord leads to neural and molecular pathophysiological responses. Biomarkers are emerging as a promising unbiased tool that can assess the pathophysiological processes following spinal cord injury (SCI). In this concise review, we provide details of role and expression of structural, including Neurofilament Proteins (NF), Glial Fibrillary Acidic Protein (GFAP), Cleaved Tau (C-Tau), S100-β, Neuron Specific Enolase (NSE), Myelin Basic Protein (MBP), and inflammatory, including Transforming Growth Factor Beta (TGF-β), Tumor Necrosis Factor (TNF), Interleukins (ILs), Soluble CD95 Ligand (sCD95L) biomarkers in reported human and animal SCI studies.

Indexed as

Animal studiesBiomarkersHuman studiesInflammatory biomarkersNeuronal injurySpinal cord injuryStructural biomarkers

Identifiers

PMID40894309
PMCPMC12393836

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.