Evidence map›Paper›PMID 40894231›Full record

ArticleFrontiers in pharmacology2025

Clinicians' view on non-adherence: sharing expert opinion.

Ngiap Chuan Tan, Shashank R Joshi, Enrique De-Madaria, Badr Eldin Mostafa, O Nuri Özgirgin, Tommaso Simoncini, Lale Tokgözoğlu

Abstract read
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Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ngiap Chuan TanSingHealth Polyclinics, Singapore, Singapore.
Shashank R JoshiJoshi Clinic, Mumbai, India.
Enrique De-MadariaDepartment of Gastroenterology, Dr. Balmis General University Hospital and Department of Clinical Medicine, Miguel Hernández University, Alicante, Spain.
Badr Eldin MostafaFaculty of Medicine, Ain Shams University, Heliopolis-Cairo, Egypt.
O Nuri ÖzgirginBayındır Sogutozu Hospital, Ankara, Türkiye.
Tommaso SimonciniDivision of Obstetrics and Gynecology, Department of Experimental and Clinical Medicine, University of Pisa, Pisa, Italy.
Lale TokgözoğluDepartment of Cardiology, Hacettepe University Medical Faculty, Ankara, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Medication non-adherence (NA) remains a persistent challenge across all medical specialties, contributing to adverse patient outcomes and increased healthcare burdens. While numerous studies have explored patient-related factors influencing adherence, the perspectives of healthcare professionals remain underrepresented in literature. This study aims to document the individual experiences of seven international physicians across diverse medical fields, highlighting barriers, detection methods, and strategies employed to address NA in their daily practice. Methodology: A structured qualitative approach was employed, incorporating semi-structured interviews and written questionnaires to capture expert insights. Seven physicians from specialties including family medicine, gastroenterology, otolaryngology, otology and neurotology, obstetrics and gynecology, endocrinology and cardiology participated in the study. Data were analyzed thematically to identify recurring patterns, specialty-specific challenges, and practical solutions implemented by clinicians. Results: Clinicians reported that NA detection primarily relied on patient self-reporting, clinical markers, and medication reconciliation. Barriers to adherence varied by specialty but commonly included polypharmacy, treatment complexity, patient skepticism, socioeconomic constraints, and asymptomatic conditions. Strategies to enhance adherence encompassed patient education, shared decision-making, therapeutic simplification, digital tools, and team-based care models. Despite proactive efforts, clinicians cited systemic limitations such as time constraints, fragmented healthcare records, and inadequate adherence-tracking mechanisms. Conclusion: Addressing NA requires a patient-centered, interdisciplinary approach integrating education, digital innovations, and structured follow-up strategies. The study underscores the necessity for larger-scale research to validate adherence interventions and refine multidisciplinary frameworks. Given the study's qualitative nature and small sample size, future research should incorporate broader datasets and diverse healthcare perspectives to develop more comprehensive adherence solutions.

Indexed as

adherence strategiesexpert opinionmedication adherencenon-adherencepatient compliance

Identifiers

PMID40894231
PMCPMC12396120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.