ArticlemedRxiv : the preprint server for health sciences2025
Who Makes It Through the Funnel? Sociodemographic Drivers of Recruitment Completion into an AI-Ready Digital Speech Bank.
Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Background: Digital recruitment methods offer promising opportunities to address persistent challenges in clinical research participation, particularly in specialized fields like neurology. However, the impact of digital approaches across different socioeconomic and demographic groups remains inadequately understood. This study analyzed participant recruitment pathways in a digital neurology research study to identify sociodemographic factors associated with participation outcomes. Methods: We conducted a longitudinal analysis of 5,846 patients invited to participate in a remote speech capture study for neurological disease research between March and July 2024. Using data from Qualtrics, PTrax, and our recording platform, we tracked participant progression through multiple recruitment checkpoints. Socioeconomic status was assessed using the Housing-based Socioeconomic Status (HOUSES) index and Area Deprivation Index (ADI). We examined associations between participation pathways and demographic factors including age, sex, geographic location, and socioeconomic indices using Kruskal-Wallis and Wilcoxon rank-sum tests. Results: Only 415 participants (7.1%) completed all study requirements. Participants from neighborhoods with higher socioeconomic disadvantage (higher ADI national ranks) were significantly less likely to express interest in initial invitations (median ADI 45.0 vs. 42.0 for responders, Conclusions: Digital recruitment methods in neurological research do not automatically overcome traditional barriers to participation and may introduce new disparities related to the digital divide. The significant associations between participation outcomes and sociodemographic factors-particularly neighborhood socioeconomic status, geographic location, age, and sex-highlight the need for targeted recruitment strategies. Researchers should implement multi-channel approaches, design age-specific engagement strategies, address geographic disparities, and consider socioeconomic factors to enhance the inclusivity and effectiveness of digital recruitment in neurological research.
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