Evidence map›Paper›PMID 40894012›Full record

ArticleResearch square2025

Peripheral Blood Mononuclear Cell Gene Expression Signatures Predict Long-term Survivorship in Canine DLBCL.

Kirthana Rao, Zechuan Rao, Angelina Huang, Scott Heston, Max Wang, Ümmügülsüm Yildiz-Altay, Fatima Qutab, Danny A Kwong, Heather L Gardner, Jillian M Richmond and 1 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Kirthana RaoUMass Chan Medical School.
Zechuan RaoUMass Chan Medical School.
Angelina HuangUMass Chan Medical School.
Scott HestonUMass Chan Medical School.
Max WangUMass Chan Medical School.
Ümmügülsüm Yildiz-AltayUMass Chan Medical School.
Fatima QutabUMass Chan Medical School.
Danny A KwongUMass Chan Medical School.
Heather L GardnerTufts University.
Jillian M RichmondTufts University.
Cheryl A LondonTufts University.

Funding

Enhancing the efficacy of immunotherapy in DLBCL using rational combination approachesU01CA224153 · NCI · TUFTS UNIVERSITY BOSTON · PI LONDON, CHERYL A · 2017 to 2021
$3.1M
Elucidating the therapeutic utility of targeting metabolic dependencies in osteosarcomaK01OD028268 · OD · TUFTS UNIVERSITY BOSTON · PI GARDNER, HEATHER LYNN · 2020 to 2024
$631k
NCI NIH HHS U01 CA224153NIH HHS K01 OD028268
6 · The paper itself

Abstract

Pet dogs spontaneously develop a form of diffuse large B cell lymphoma (DLBCL) that recapitulates many of the features of double hit (

Indexed as

cancer immunotherapycanine (dog)Diffuse large B cell lymphoma (DLBCL)immune landscapeinterferon (IFN)liquid/blood biopsy

Identifiers

PMID40894012
PMCPMC12393498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.