Evidence map›Paper›PMID 40893937›Full record

ArticleFrontiers in genetics2025

New therapeutic targets for endometriosis predicted through mendelian randomization analysis and case-control trials.

Linyao Zheng, Yue Yin, Xiaotong Wang, Baoju Wang, Ran Cui, Guangmei Zhang

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Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linyao ZhengDepartment of Gynaecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yue YinDepartment of Gynaecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xiaotong WangDepartment of Obstertrics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Baoju WangDepartment of Gynaecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Ran CuiDepartment of Gynaecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Guangmei ZhangDepartment of Gynaecology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Endometriosis is a common chronic gynecological condition that affects approximately 10% of women of reproductive age worldwide. Methods: This study utilized large-scale genome-wide association study data and explored the causal relationship between blood metabolites, plasma proteins, and endometriosis via Mendelian randomization and colocalization analysis methods. Clinical pathological data were collected, and hypotheses were validated through experiments such as ELISA, RT-qPCR, and Western blotting. Results: Discussion: These results suggest that

Indexed as

drug target predictionendometriosismendelian randomizationplasma proteinsRspo3

Identifiers

PMID40893937
PMCPMC12394149

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.