ArticleFrontiers in medicine2025
Prevalence and influencing factors of oral frailty among middle-aged and older patients with chronic kidney disease: a cross-sectional study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Denture hygiene knowledge, cleaning practices, and denture stomatitis among primary care patients in Alkharj, Saudi Arabia: compliance predictors, barriers and educational preferences: a cross-sectional study.Frontiers in medicine · 2026Article
- Machine learning for oral frailty factors in hospitalized schizophrenia patients: two-stage feature selection and SHAP analysis.Frontiers in psychiatry · 2026Article
- Prevalence and associated factors of oral frailty in elderly patients undergoing elective surgery: a secondary analysis of a cross-sectional study.Frontiers in medicine · 2026Article
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7 authors.
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Abstract
Background: Oral health has emerged as a subject of significant public concern. Oral frailty represents the clinical presentation of advanced oral health decline and serves as a significant indicator of systemic frailty. However, current research on oral frailty in patients with chronic kidney disease (CKD) is quite limited. Objectives: This study aimed to investigate the prevalence and influencing factors of oral frailty among middle-aged and older CKD patients. Methods: This was a cross-sectional study involving 307 CKD patients from two tertiary general hospitals in Chengdu, Sichuan Province, from November 2024 to March 2025. The Oral Frailty Index-8 (OFI-8), Mini Nutritional Assessment Short-Form (MNA-SF), Revised Piper Fatigue Scale (RPFS) and Hospital Anxiety and Depression Scale (HADS) were used to assess CKD patients. Chi-square tests and logistic regression analyses were used to determine the associated factors of oral frailty among CKD patients. Results: The prevalence of oral frailty among CKD patients was 61.9% (190/307). In binary logistic regression analysis, marital status, educational level, self-care ability, dentures, dry mouth, and the RPFS-CV score were identified as factors significantly increasing the risk of oral frailty in middle-aged and older hospitalized patients with CKD. Conclusion: Compared with non-CKD patients, CKD patients demonstrate poorer oral health status, and oral frailty is common among CKD patients. This finding suggests the necessity for healthcare professionals to develop individualized and evidence-based strategies for the prevention and management of oral frailty, with particular emphasis on high-risk populations requiring targeted interventions.
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