ArticleFrontiers in medicine2025
Differential diagnosis between psoriatic arthritis and hand osteoarthritis using indocyanine green-based fluorescence optical imaging.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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10 authors.
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Abstract
Introduction: Fluorescence optical imaging (FOI) visualizes enhanced microcirculation in the hands as a marker for inflammation. The correct diagnosis of psoriatic arthritis (PsA) and erosive hand osteoarthritis (EHOA) can be challenging. The aim of this study was to differentiate active PsA from EHOA using FOI. Methods: An atlas with FOI images of different grades of enhancement (FOIAS 0-3) and typical morphologic patterns ('Streaky signals', 'Green/Blue Nail sign', 'Werner sign', and 'Bishop's crozier sign') for PsA and hand EHOA was created. Twenty FOI sequences of patients with PsA and EHOA were randomly mixed and scored by two blinded readers. All images were scored twice by one of the two readers. Inter- and intra-reader reliability for joint enhancement, morphologic patterns and diagnosis (PsA vs. EHOA) was calculated. Subsequently, one reader blinded to the diagnosis scored the remaining PsA ( Results: Inter-reader reliability on joint enhancement was overall substantial ( Conclusion: Joint enhancement in FOI can be reliably assessed using a predefined scoring method. The stronger enhancement in PIP and DIP joints for EHOA cases and the occurrence of 'Werner sign' in PsA cases may facilitate the differential diagnosis between the two diagnoses.
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