Evidence map›Paper›PMID 40893737›Full record

ArticleF1000Research2025

Silent Danger: Risk Factors and Outcomes of Fortuitously Discovered Uterine Rupture - A 41-Case Cohort Study.

Narjes Karmous, Siwar Ghrab, Abdelwahab Masmoudi, Badreddine Bouguerra, Aymen Mabrouk, Anis Ben Dhaou, Abdennour Karmous

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Article in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Narjes KarmousDepartment B of Obstetrics and Gynecology, Charles Nicolle Hospital, Tinis, Tunisia.ORCID https://orcid.org/0009-0001-9101-7849
Siwar GhrabDepartment B of Obstetrics and Gynecology, Charles Nicolle Hospital, Tinis, Tunisia.
Abdelwahab MasmoudiDepartment B of Obstetrics and Gynecology, Charles Nicolle Hospital, Tinis, Tunisia.
Badreddine BouguerraDepartment B of Obstetrics and Gynecology, Charles Nicolle Hospital, Tinis, Tunisia.
Aymen MabroukGeneral surgery department B, Charles Nicolle Hospital, Tunis, Tunisia.
Anis Ben DhaouGeneral surgery department B, Charles Nicolle Hospital, Tunis, Tunisia.
Abdennour KarmousPsychiatry Department, Razi Hospital, Manouba, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Uterine rupture (UR) remains a major cause of maternal morbidity, especially in low-resource settings. While typically detected during labor, some cases are clinically silent, discovered incidentally during imaging/surgery, highlighting a knowledge gap in risk assessment. In Tunisia, 1.5% of pregnancies involve UR, mostly scar-related. The study aim was to identify factors associated with the development of fortuitously discovered UR in cases that were incidentally found during pregnancy or delivery. Methods: This was retrospective, longitudinal cohort study conducted over an eleven-year period, from January 2014 to December 2024, at the Gynaecology and Obstetrics department B, Charles Nicolle Hospital, Tunis, Tunisia. Asymptomatic UR cases (complete/incomplete) were analysed to compare clinical profiles, identify risk factors, and assess maternal and neonatal outcomes. Results: A total of 41 cases of asymptomatic UR were included, which accounted for an average of 50% of the UR cases. In a cohort comparing complete UR cases (N=27) and incomplete UR cases (N=14), significant differences in duration of pregnancy and labor were found. The mean gestational age was longer in the incomplete UR group (p=0.03), and the duration of labor was also significantly longer (p=0.006). No significant differences were observed in sociodemographic characteristics, quality of prenatal care, or complications such as gestational diabetes or preeclampsia. Nonsignificant factors included pregnancy interval, scars number and labor stagnation. The analysis showed two significant predictors of complete UR outcomes. Prolonged labor (>220 minutes) was strongly associated with increased odds of complete UR (OR=45.231, 95% CI=2.591-789.486, p=0.009) and lower maternal weight (<68 kg) correlated with reduced odds of incomplete UR (OR=0.033, 95% CI=0.001-0.837, p=0.039), suggesting a protective effect per kilogram maternal body weight decrease. Conclusion: Findings redefine UR as part of a broader clinical spectrum, not just an acute obstetric complication. Early identification of associated risk factors such as prolonged labor and maternal weight could inform targeted surveillance in high-risk pregnancies.

Indexed as

Uterine RuptureAdultCohort StudiesFemaleHumansLongitudinal StudiesPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsTunisia"Incidental diagnosis""Post-cesarean delivery complications""Scarred uterus""Silent uterine rupture""Third-trimester obstetric emergencies"."Uterine rupture"

Identifiers

PMID40893737
PMCPMC12395129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.