ReviewARYA atherosclerosis2025
Clinical insights into nonbacterial thrombotic endocarditis in cancer patients: A case-based systematic review.
Review in ARYA atherosclerosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Cardiac valve mass revealed by venous and arterial embolism: case report and review of the literature.European heart journal. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNonbacterial thrombotic endocarditis (NBTE) is a rare yet critical complication in cancer patients, with high embolic risk and poor prognoses. This systematic review investigates the clinical presentation, valve involvement, embolic risk, vegetation management, and prognostic variability across cancer types in NBTE cases.
methodsAdhering to PRISMA guidelines, we conducted a comprehensive literature search in PubMed, Scopus, and Embase for studies from 2000 to September 2024. Extracted data included demographics; cancer type and site; NBTE diagnosis timing; valve characteristics; embolic events; and patient outcomes. Chi-square and regression analyses evaluated associations among clinical variables and outcomes. Quality was appraised using the Joanna Briggs Institute tool.
resultsFrom 38 studies comprising 40 cases, the mean patient age was 50.5 years (±12.5), with equal gender distribution (20 males, 20 females). Pancreatic adenocarcinoma (17.5%) and lung adenocarcinoma (15.0%) were most frequently associated with NBTE. Mortality rates varied significantly by cancer type, with gastrointestinal and urogenital cancers showing the highest rates. A significant association was found between cancer type and vegetation management strategy (χ² = 24.41, p = 0.018). Further correlations indicated that longer cancer histories necessitated more invasive management, and concurrent embolic events correlated with poorer prognoses. Quality assessment reinforced the findings' reliability (65% high quality).
conclusionNBTE in cancer patients shows distinct clinical and prognostic patterns, with cancer type impacting both management and outcomes. These insights highlight the importance of tailored management approaches and provide a basis for future research to enhance care and prognostic assessments in NBTE cases within oncology.
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