Evidence map›Paper›PMID 40893633›Full record

ReviewJHLT open2025

Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension: Technical challenges and controversies.

Tom Verbelen, Elie Fadel, Christoph B Wiedenroth, David P Jenkins, Michael M Madani

Abstract readReview
In one paragraph

Review in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tom VerbelenDepartment of Cardiac Surgery, University Hospitals Leuven and Department of Cardiovascular Sciences, KU Leuven-University of Leuven, Leuven, Belgium.
Elie FadelThoracic Surgery, Marie Lannelongue Hospital, Paris-Saclay University, Le Plessis Robinson, France.
Christoph B WiedenrothKerckhoff Heart and Thorax Center, Department of Thoracic Surgery, Bad Nauheim, Germany.
David P JenkinsCardiothoracic Surgery, Royal Papworth Hospital, Cambridge, United Kingdom.
Michael M MadaniCardiovascular and Thoracic Surgery, University of California San Diego, La Jolla, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic thromboembolic pulmonary hypertension requires referral to an expert center for final diagnosis and assessment of treatment possibilities by a multidisciplinary team. Pulmonary endarterectomy is the only potentially curative therapy and therefore remains the treatment of choice. However, many practices and minor technical aspects of this procedure may still provoke controversy. Based on the most recent literature and the author's own experiences and opinions, and in lack of clear guidelines, this review discusses the rationale for blood management strategies; practices during deep hypothermic circulatory arrest; concomitant surgical procedures; pulmonary endarterectomy in specific patient populations, in redo setting and for other diseases; the role of balloon pulmonary angioplasty and of minimal access techniques; and the required surgical expertise. Well-founded recommendations can only be made for a few of them.

Indexed as

chronic thromboembolic pulmonary hypertension (CTEPH)deep hypothermic circulatory arrest (DHCA)multimodality treatmentpulmonary endarterectomy (PEA)surgical expertise

Identifiers

PMID40893633
PMCPMC12396025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.