Evidence map›Paper›PMID 40893632›Full record

ArticleJHLT open2025

Challenges in medication titration in children with heart failure.

Jessie Yester, Deipanjan Nandi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jessie YesterThe Heart Center, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.
Deipanjan NandiThe Heart Center, Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of pediatric heart failure and titration of oral medical therapies remains in its infancy. Burdened by a lack of understanding of the diverse pediatric heart failure etiologies, limitations in clinical trials, a lack of society guidelines, as well as other health care systemic issues, titration of medications is greatly lacking. We herein review the difficulties with medication titration in pediatric heart failure, and highlight important next steps to remedy the situation.

Indexed as

cardiomyopathyguidelinesheart failurepediatricstitration

Identifiers

PMID40893632
PMCPMC12391281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.