ArticleQuantitative imaging in medicine and surgery2025
Feasibility and reliability of high-resolution phase-contrast quantitative-flow magnetic resonance imaging for assessing femoral head blood flow: a prospective study.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The early identification of abnormal blood supply to the femoral head is crucial for timely intervention. High-resolution phase-contrast quantitative-flow (Q-flow) magnetic resonance imaging (MRI) is a promising non-invasive technique for quantitatively assessing blood flow to the femoral head. This study aimed to evaluate the feasibility and reliability of Q-flow in quantifying blood flow to the femoral head. Methods: This prospective study included 10 healthy volunteers (mean age =35±8.38 years, 6 women), 10 women with systemic lupus erythematosus (SLE), who were using corticosteroids (mean age =36.1±5.47 years), and 10 age-matched healthy women for the SLE patients, who served as controls (mean age =36.2±4.83 years). Q-flow scans were performed on all the participants from October 2023 to August 2024. Q-flow reliability, including retest reliability between scans, and intra- and inter-rater reliability, was evaluated using data from the healthy volunteers. Further, the efficacy of Q-flow was evaluated by comparing the quantification data between the SLE and control groups. Results: Q-flow showed good-to-excellent reliability for the arterial flow parameters [intra-class correlation coefficient (ICC): 0.61-1], except for the regurgitant fraction (RF; ICC: 0.01-0.97). Q-flow also showed good-to-excellent reliability for the vein flow parameters (ICC: 0.63-1), except for the retest reliability of the RF (ICC: 0.04-0.9), mean velocity (MV; ICC: 0.46-0.84), and peak systolic velocity (PSV; ICC: 0.5-0.73). Compared with the controls, the SLE patients had significantly reduced arterial flow in the medial femoral circumflex artery (MFCA) [stroke and stroke distance (SD), P=0.01 and P<0.01], lateral femoral circumflex artery (LFCA) [stroke, mean flux (MF), SD, MV, and PSV, all P<0.01], and deep MFCA (stroke, MF, SD, MV, and PSV, all P<0.01). Conclusions: The high-resolution phase-contrast Q-flow technique exhibited acceptable reliability and the capacity to detect early changes in arterial blood flow to the femoral head, highlighting its potential clinical applicability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.