ArticleQuantitative imaging in medicine and surgery2025
Reduced pulmonary vascular bed volume in cryptogenic stroke patients with patent foramen ovale: a myocardial contrast echocardiography study.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Pulmonary vascular bed volume (PVBV) in cryptogenic stroke patients with patent foramen ovale (PFO) has not been well characterized. This study examined PVBV in cryptogenic stroke patients with suspected PFO. Methods: A total of 469 patients underwent agitated saline contrast transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) between January 2021 and December 2024. PVBV was quantified by myocardial contrast echocardiography (MCE). Results: Of the included patients, 423 were diagnosed with PFO, and 46 served as controls. The PFO group demonstrated elevated pulmonary vascular resistance (PVR) and reduced right ventricular systolic function (all P<0.05), with significantly reduced PVBV compared to controls [242.89 (202.91-465.05) Conclusions: PVBV is reduced in cryptogenic stroke patients with PFO, and right-to-left shunt level, BSA, and gender were the factors associated with PVBV. Addressing these gaps could enhance the understanding of cardiopulmonary interactions in PFO.
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