ArticleQuantitative imaging in medicine and surgery2025
Quantitative analysis of macular and optic disc microvascular parameters in patients with immunoglobulin A nephropathy using optical coherence tomography angiography.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Investigating Retinal Microvascular Changes Using OCT-Angiography: The Role of Oxidative Stress and Endothelial Dysfunction in Hypertensive Nephropathy.Medicina (Kaunas, Lithuania) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Immunoglobulin A nephropathy (IgAN) is a common chronic glomerulonephritis. The kidneys and eyes have structural and developmental similarities, but ocular microvascular changes in IgAN, especially in the macular and optic disc, are poorly studied. This study aimed to assess these microvascular parameters in IgAN patients using optical coherence tomography (OCT) and OCT angiography (OCTA) and explore their associations with clinical data. Methods: This is a case-control study. Fifteen patients with IgAN and 15 healthy controls (HCs) who attended The Affiliated Hospital of Southwest Medical University between July 2022 and December 2023 were selected. OCT and OCTA were used to assess macular thickness, retinal nerve fiber layer (RNFL) thickness, the vascular density (VD) and perfusion density (PD) of macular and optic disc, and foveal avascular zone (FAZ). In addition, we analyzed the association between OCT and OCTA parameters and clinical data in patients with IgAN. Results: VD and PD were significantly lower in the macular area in the IgAN group than the HCs (VD: 18.270±0.683 Conclusions: Compared with HCs, the status of macular microcirculation in the IgAN group was significantly decreased, and some microvascular parameters were significantly correlated with the clinical data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.