Evidence map›Paper›PMID 40893403›Full record

ArticleNature catalysis2025

Enantioselective Pd-Catalysed Nucleophilic C(sp

Nikita Chekshin, Luo-Yan Liu, D Quang Phan, David J Donnelly, Yuxin Ouyang, Kap-Sun Yeung, Jennifer X Qiao, Jin-Quan Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature catalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nikita ChekshinDepartment of Chemistry, The Scripps Research Institute; 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Luo-Yan LiuDepartment of Chemistry, The Scripps Research Institute; 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
D Quang PhanDepartment of Chemistry, The Scripps Research Institute; 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
David J DonnellySmall Molecule Drug Discovery, Bristol-Myers Squibb Research and Development; P.O. Box 4000, Princeton, New Jersey 08543, USA.
Yuxin OuyangDepartment of Chemistry, The Scripps Research Institute; 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Kap-Sun YeungSmall Molecule Drug Discovery, Bristol-Myers Squibb Research and Development; 250 Water Street, Cambridge, MA 02141, USA.
Jennifer X QiaoSmall Molecule Drug Discovery, Bristol-Myers Squibb Research and Development; 250 Water Street, Cambridge, MA 02141, USA.
Jin-Quan YuDepartment of Chemistry, The Scripps Research Institute; 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Funding

Ligand-promoted Enantioselective C-H Activation ReactionsR01GM084019 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI YU, JIN-QUAN · 2008 to 2024
$9.5M
NIGMS NIH HHS R01 GM084019
6 · The paper itself

Abstract

Despite increasing demand for chiral fluorinated organic molecules, enantioselective C-H fluorination remains among the most challenging and sought-after transformations in organic synthesis. Furthermore, utilizing nucleophilic sources of fluorine is especially desirable for

Identifiers

PMID40893403
PMCPMC12393139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.