ArticleSchizophrenia research. Cognition2025
Symptom severity and cognitive performance in patients with substance induced psychotic disorder and schizophrenia: a cross-sectional comparative study.
Article in Schizophrenia research. Cognition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and hypothesis: psychotic disorders induced by substances like marijuana, amphetamines and methamphetamines (SIPDs) are a growing mental health problem, yet the question do they represent a separate psychotic class independent from schizophrenia (SZ) still stands. Studies comparing clinical and cognitive performance of SIPD and SZ patients have produced inconsistent results. Study design: we performed a cross-sectional analysis of 62 subjects divided into two statistically matched groups ( Study results: SZ subjects had significantly higher positive and negative PANSS scores and greater impairment in all cognitive domains except semantic memory and language (VFT). Compared to the normative values of all tests both SZ and SIPD patients performed poorer. Conclusions: Our data support the assumption that the two conditions share a common underlying neurobiological vulnerability that is more pronounced quantitatively in schizophrenia.
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