Evidence map›Paper›PMID 40893234›Full record

ArticleACS omega2025

Palladium-Catalyzed C-H Arylation of Quinoidal Scaffolds Through Homogeneous and Heterogeneous Pathways: Advancing Toward Trypanocidal Prototypes.

José M C Tavares Junior, Eduardo F S Guimarães, Mateus P Nunes, Renata G Almeida, Maria H Araujo, Victor F S Ramos, Rubem F S Menna-Barreto, Joel A Tchuiteng Kouatchou, Edmond Gravel, Eric Doris and 2 more

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Fluorination of amino-quinones enhances anti-RSC medicinal chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

José M C Tavares JuniorDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Eduardo F S GuimarãesDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Mateus P NunesDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.ORCID https://orcid.org/0000-0003-4796-3448
Renata G AlmeidaDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.ORCID https://orcid.org/0000-0003-2896-0487
Maria H AraujoDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Victor F S RamosLaboratório de Biologia Celular, IOC, FIOCRUZ, Rio de Janeiro, Rio de Janeiro 21045-900, Brazil.
Rubem F S Menna-BarretoLaboratório de Biologia Celular, IOC, FIOCRUZ, Rio de Janeiro, Rio de Janeiro 21045-900, Brazil.
Joel A Tchuiteng KouatchouDépartement Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SCBM, Gif-sur-Yvette 91191, France.
Edmond GravelDépartement Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SCBM, Gif-sur-Yvette 91191, France.ORCID https://orcid.org/0000-0001-6077-1016
Eric DorisDépartement Médicaments et Technologies pour la Santé (DMTS), Université Paris-Saclay, CEA, INRAE, SCBM, Gif-sur-Yvette 91191, France.ORCID https://orcid.org/0000-0003-1318-602X
Guilherme A M JardimDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.ORCID https://orcid.org/0000-0002-9882-3085
Eufrânio N da Silva JúniorDepartamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.ORCID https://orcid.org/0000-0003-1281-5453

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A Pd-mediated C-H activation methodology was developed for the direct arylation of quinoidal skeletons, both by means of homogeneous catalysis and heterogeneous catalysis using metal-decorated carbon nanotubes, enabling the direct functionalization of quinones in moderate to excellent yields. The derivatives obtained were tested against trypomastigote forms of

Identifiers

PMID40893234
PMCPMC12391934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.