Evidence map›Paper›PMID 40893233›Full record

ArticleACS omega2025

Evaluation of the Therapeutic Efficacy of the Newly Formulated Drug "Novostron" as an Experimental Basis for Clinical Trials.

Nailya Ibragimova, Aisulu Kabdraisova, Marina Lyu, Zhanar Iskakbayeva, Arkadiy Krasnoshtanov, Yuliya Tin, Sakhipov Yermek, Seitzhan Turganbay, Roza Karzhaubayeva, Aleksander Ivanovich Ilin and 3 more

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nailya IbragimovaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Aisulu KabdraisovaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Marina LyuJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Zhanar IskakbayevaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Arkadiy KrasnoshtanovJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Yuliya TinJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Sakhipov YermekJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Seitzhan TurganbayJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Roza KarzhaubayevaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Aleksander Ivanovich IlinJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Amirkan AzembayevJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Serzhan MombekovJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Republic of Kazakhstan.
Saki RaheemSchool of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, U.K.ORCID https://orcid.org/0000-0003-1691-4483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wound infections driven by multidrug-resistant (MDR) bacteria continue to challenge modern medicine. This study introduces "Novostron", an innovative topical iodine-based formulation incorporating dextrin and metal halides designed to overcome the limitations of existing antiseptics, such as volatility and cytotoxicity. The complex's physicochemical properties were analyzed using infrared (IR) and ultraviolet (UV) spectroscopy, alongside thermogravimetric analysis, confirming its stability and robust iodine retention. Stability assessments revealed minimal iodine loss under optimal refrigerated conditions. In a rat skin wound model, the microbial load was significantly reduced to 1.4 ± 0.5 CFU/cm

Identifiers

PMID40893233
PMCPMC12392178

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.