Evidence map›Paper›PMID 40893085›Full record

ArticleHealth affairs (Project Hope)2025

Geography And Fentanyl: Explaining The Disproportionate Rise In Opioid Overdose Deaths Among Black Americans.

David Powell, Dan Han, Jevay Grooms, Rosalie Liccardo Pacula

Abstract read
In one paragraph

Article in Health affairs (Project Hope), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Fentanyl Purity and Overdose Decline: A Reexamination of Geographic Trends.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David PowellDavid Powell (David.Powell@PennMedicine.upenn.edu), University of Pennsylvania, Philadelphia, Pennsylvania.
Dan HanDan Han, National University of Singapore, Singapore.
Jevay GroomsJevay Grooms, Howard University, Washington, D.C.
Rosalie Liccardo PaculaRosalie Liccardo Pacula, University of Southern California, Los Angeles, California.

Funding

Optimal Methods for Estimating Policy Effect Heterogeneity in Opioid Policy ResearchP50DA046351 · NIDA · RAND CORPORATION · PI Rosanna Smart · 2018 to 2026
$20.8M
Understanding cannabidiol policy and its impacts on broader substance useR21DA060486 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI David Powell · 2025 to 2026
$457k
NIDA NIH HHS P50 DA046351NIDA NIH HHS R21 DA060486
6 · The paper itself

Abstract

This study investigated how geography helps explain the striking increase in opioid-related overdose deaths among Black Americans since the proliferation of fentanyl. Using mortality data from the period 1999-2020, we modeled annual overdose rates as a function of race and ethnicity and county of residence to identify the share of racial differences in overdose rate growth that could be attributed to location. Geographic incidence contributed little to racial and ethnic overdose disparities before 2013 but became an important factor during the fentanyl crisis. Between 2010 and 2020, roughly 40 percent of the additional growth in Black opioid-related overdoses versus White overdoses was attributable to differential geographic exposure to the fentanyl crisis. Overdoses involving opioids but not cocaine are largely attributed to geography, whereas overdoses involving both opioids and cocaine show a smaller geographic component. These findings underscore a possible role for place-based interventions to affect racial and ethnic disparities in overdose rates.

Indexed as

Analgesics, OpioidBlack or African AmericanDrug OverdoseFentanylOpiate OverdoseAdultFemaleGeographyHumansIncidenceMaleUnited StatesAnalgesics, OpioidFentanyl

Identifiers

PMID40893085
PMCPMC13284975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.