Evidence map›Paper›PMID 40892269›Full record

ReviewNeuroradiology2025

Stent-Assisted Coil Embolization Versus Flow Diversion in Intracranial Vertebral Artery Dissecting Aneurysms: A Systematic Review and Meta-Analysis.

Ocílio Ribeiro Gonçalves, Anderson Matheus Pereira da SIlva, Mariana Lee Han, Filipe Virgilio Ribeiro, Mariana Oliveira, Rafael Reis de Oliveira, Milene Vitória Sampaio Sobral, Ahmet Gunkan, Marcio Yuri Ferreira, Jhon E Bocanegra-Becerra and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ocílio Ribeiro GonçalvesFederal University of Piauí, Teresina, Brazil. ocilio41@gmail.com.
Anderson Matheus Pereira da SIlvaFederal University of Pernambuco, Recife, Brazil. anderson.mhps@icloud.com.
Mariana Lee HanUniversidade de São Paulo, São Paulo, Brazil.
Filipe Virgilio RibeiroBarão de Mauá University Center, Ribeirão Preto, Brazil.
Mariana OliveiraCollege of Higher Education of the United Amazon, Pará, Brazil.
Rafael Reis de OliveiraFederal University of Para, Belém, Brazil.
Milene Vitória Sampaio SobralUniversidade do Oeste Paulista, Presidente Prudente, Brazil.
Ahmet GunkanUnidade General Osório, Nova Friburgo, Brazil.
Marcio Yuri FerreiraNorthwell, New Hyde Park, New York, USA.
Jhon E Bocanegra-BecerraCayetano Heredia University, Lima, Peru.
Christian FerreiraPhelps Hospital, Sleepy Hollow, USA.
David GordonPhelps Hospital, Sleepy Hollow, USA.
Yafell SerulleNorthwell, New Hyde Park, New York, USA.
David LangerNorthwell, New Hyde Park, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntracranial vertebral artery dissecting aneurysms (IVADAs) represent a rare but challenging condition associated with high morbidity and mortality. In the therapeutic landscape, endovascular interventions such as Flow Diversion (FD) and Stent-Assisted Coiling (SAC) are widely used for the management of IVADAs. The aim of this systematic review and meta-analysis is to compare the clinical outcomes and complications associated with FD and SAC techniques in the endovascular management of IVADAs.

methodsWe systematically searched PubMed, Embase, Web of Science and Scopus from inception to December 2024. This meta-analysis included retrospective cohort studies comparing flow diverters versus stent-assisted coiling in patients with IVADAs. The primary outcomes included in-stent stenosis, complete occlusion rates, and modified Rankin Scale (mRS) scores. Risk of bias was assessed using the ROBINS-I tool for non-randomized studies. Statistical analyses were conducted using R software (version 4.4.0), with risk ratios (RR) and 95% confidence intervals (CI) calculated using the Mantel-Haenszel method. Heterogeneity was assessed using Cochran's Q test and I

resultsA total of seven non-randomized studies were included in the meta-analysis comprising 649 patients with IVADAs. Long-term complete occlusion rates were similar between FD and SAC (RR 0.99; 95% CI 0.89-1.10; I

conclusionIn this meta-analysis, FD and SAC demonstrated comparable efficacy and safety profiles in the treatment of IVADAs, with no significant differences in long-term complete occlusion, recurrence, retreatment, in-stent stenosis, or complication rates. In this context, FD is a promising technique to treat IVADAs.

Indexed as

EndovascularFlow diversionIntracranial vertebral artery dissecting aneurysmsMeta-analysisPosterior circulation aneurysmsStent-assisted coil

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.