Evidence map›Paper›PMID 40892265›Full record

SynthesisArchives of orthopaedic and trauma surgery2025

Patient self-reported outcomes 10 years after surgical correction in AIS patients. A systematic review and meta-analysis.

Eduardo Hevia, Jesús Burgos, Ignacio Sanpera, Vicente García, María Teresa de Santos Moreno, María Benlloch, Gonzalo Mariscal, Carlos Barrios

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eduardo HeviaSpine Unit, University of Navarra Clinic, Madrid, Spain.
Jesús BurgosVithas Internacional, Madrid, Spain.
Ignacio SanperaPediatric Orthopedics, Son Espases Hospital, Palma de Mallorca, Spain.
Vicente GarcíaSpine Surgery Section, Araba University Hospital, Vitoria, Spain.
María Teresa de Santos MorenoNeuropediatrics Unit, San Carlos Clinic Hospital, Madrid, Spain.
María BenllochDepartment of Basic Medical Sciences, Catholic University of Valencia San Vicente Mártir, Valencia, Spain.
Gonzalo MariscalMediterranean Observatory for Clinical and Health Research (OMEDICS), Valencia, Spain. Gonzalo.mariscal@mail.ucv.es.ORCID http://orcid.org/0000-0002-5166-198X
Carlos BarriosInstitute for Research on Musculoskeletal Disorders, School of Medicine, Valencia Catholic University, Carrer de Quevedo, 2, Valencia, 46001, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionthe aim of this report is to evaluate the long-term (≥ 10 years) functional outcomes and quality of life after surgery in AIS patients.

methodsPROSPERO (CRD42023439331). Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Systematic Review (PRISMA) guidelines were followed. The PubMed, EMBASE, Scopus, and Cochrane Collaboration Library databases were used. Comparative studies assessing outcomes ≥ 10 years after surgery in AIS patients and controls were included. Study quality was assessed using the MINORS criteria. The outcomes of interest were SRS-22/24 scores for pain, self-image, function, mental health, total score, and the Oswestry Disability Index (ODI). Comparisons were performed using mean difference (MD) with 95% confidence interval (CI). Heterogeneity was assessed using the I2 statistic. A fixed effects model was used if there was no evidence of heterogeneity.

resultsFour comparative cohort studies and four case series were analyzed (n = 586). At long-term follow-up, pain (MD -0.47, 95%CI -0.64 to -0.30), self-image (MD -0.45, 95%CI -0.62 to -0.28), function (MD -0.45, 95%CI -0.83 to -0.07), and mental health (MD -0.53,95%CI -0.84 to -0.23) SRS-22 domains were significantly lower in surgically treated AIS patients than in controls. The total SRS score (MD -0.38, 95%CI -0.58 to -0.17) and ODI scores (MD 3.12, 95%CI 0.51 to 5.73) were lower in surgically treated patients. No significant differences were noted pre- and postoperatively ≥ 10 years after surgery in pain (MD -0.05,95%CI -0.32 to 0.23) and function (MD -0.05,95%CI -0.30 to 0.21), while self-image (MD -0.68,95%CI -1.02 to -0.34) and mental health (MD -0.37,95%CI -0.99 to 0.25) improved.

conclusionTen years or more after surgery, patients with AIS had a significantly lower quality of life and higher disability than their healthy peers, based on lower SRS scores in multiple domains and higher ODI, except for self-image and mental health that improved.

Indexed as

Patient Reported Outcome MeasuresScoliosisHumansQuality of LifeAdolescent idiopathic scoliosisLong-termMeta-analysisPatient reported outcomesQuality of life

Identifiers

PMID40892265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.