Evidence map›Paper›PMID 40892203›Full record

ArticleOral radiology2026

Treatment response assessment in resistant oral squamous cell carcinoma applying

Mai Kim, Masaru Ogawa, Keisuke Suzuki, Azusa Tokue, Tetsuya Higuchi, Yoshito Tsushima, Satoshi Yokoo

Abstract read
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In one paragraph

Article in Oral radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mai KimDepartment of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan. kimmu@gunma-u.ac.jp.
Masaru OgawaDepartment of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.
Keisuke SuzukiDepartment of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.
Azusa TokueDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.
Tetsuya HiguchiDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.
Yoshito TsushimaDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.
Satoshi YokooDepartment of Oral and Maxillofacial Surgery, and Plastic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.

Funding

Japan Society for the Promotion of Science 21K09838
6 · The paper itself

Abstract

objectiveThe present study examined the efficacy of the PATIENTS AND

methodsWe included 29 oral squamous cell carcinoma (OSCC) patients with disease progression post the primary treatment, who had

resultsPatients were categorized into a responder group (n = 7) and non-responder group (n = 22). A univariate analysis revealed significant differences in the CT maximum diameter and metabolic tumor volume (p = 0.050, and 0.037, respectively). A multivariate Cox regression analysis revealed a correlation (hazard ratio 3.59, p = 0.046, 95% confidence interval 1.02-12.6) between Lugano-OC and the duration of treatment responses.

conclusionAmong OSCC patients with disease progression post the primary treatment, those with Lugano-OC-localized disease who received radiation chemotherapy had a significantly longer treatment response than patients with advanced-stage disease. These results suggest the predictive value of Lugano-OC for assessing treatment responses in this patient population.

Indexed as

Carcinoma, Squamous CellFluorodeoxyglucose F18Mouth NeoplasmsPositron Emission Tomography Computed TomographyAdultAgedAged, 80 and overDisease ProgressionFemaleHumansMaleMiddle AgedNeoplasm StagingRadiopharmaceuticalsRetrospective StudiesTreatment OutcomeFluorodeoxyglucose F18Radiopharmaceuticals18F-FDG PET/CTLugano classificationOSCC

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.