Evidence map›Paper›PMID 40892190›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2026

Tough versus soft regulations to promote generic medications in Italy.

Aarushi Dhingra, Gianluca Fiorentini, Ayman Fouda, Naomi Moy

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aarushi DhingraDepartment of Economics, University of Bologna, Bologna, Italy. aarushi.aarushi@unibo.it.ORCID http://orcid.org/0000-0002-3719-4414
Gianluca FiorentiniDepartment of Economics, University of Bologna, Bologna, Italy.
Ayman FoudaMCI Management Center Innsbruck, Innsbruck, Austria.
Naomi MoyDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper investigates the effects of regulations aiming to optimise the multi-agency relationships, with a focus on the prescription choice between generic versus branded medications. In 2012, Italian legislators introduced two laws targeting general practitioners prescription behaviour, a soft (recommendations) law followed by a hard (mandatory) law to promote generic medication. We implement a regression discontinuity in time framework and an event study to quarterly administrative data for individuals with chronic kidney disease linked to data from their general practitioners in Emilia-Romagna, Italy. The results indicate that the policies were effective, but had modest effects on increasing the prescription of generic medications. Hard laws seem to have played a key role in driving this change. Heterogeneity checks provide evidence that less competition among GPs and interaction with specialists increased generic medication prescriptions.

Indexed as

Drugs, GenericPractice Patterns, Physicians'AgedFemaleGeneral PractitionersHumansItalyMaleMiddle AgedRenal Insufficiency, ChronicDrugs, GenericChronic kidney diseaseGeneric drugsMedication-naivetyMulti-agent problemPrescription decision

Identifiers

PMID40892190
PMCPMC13046631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.