Evidence map›Paper›PMID 40892160›Full record

ArticleCA: a cancer journal for clinicians

Prostate cancer statistics, 2025.

Tyler B Kratzer, Natalia Mazzitelli, Jessica Star, William L Dahut, Ahmedin Jemal, Rebecca L Siegel

2 registry-linked trialsAbstract read
In one paragraph

Article in CA: a cancer journal for clinicians. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 125 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07485881 not yet recruitingnot on this map

18F-PSMA PET/CT Versus CT Alone in Initial Staging, Assessment of Therapy Response and Evaluation of Biochemical Recurrence in Prostatic Cancer Patients

TypeobservationalSponsorAssiut UniversityRan2026 to 2028Enrolled59ConditionsProstate Cancer, Prostate Cancer Metastatic, Prostate Cancer Recurrent
NCT07631806 active not recruitingnot on this map

Prospective Validation of an AI-Assisted Multimodal Imaging-Pathology Fusion System for Precision Diagnosis and Biopsy Guidance in Patients With Suspected Prostate Cancer

TypeobservationalSponsorGuangxi Medical UniversityRan2026 to 2028Enrolled500ConditionsProstate Cancer With PSA Gray Zone
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tyler B KratzerSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.ORCID 0000-0002-5618-6380
Natalia MazzitelliSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.ORCID 0009-0008-4168-5030
Jessica StarSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.ORCID 0000-0003-3522-9609
William L DahutSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.ORCID 0000-0002-2766-9703
Ahmedin JemalSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.
Rebecca L SiegelSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.ORCID 0000-0001-5247-8522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the most common cancer among men in the United States, and the incidence of advanced disease is increasing rapidly. This article provides an overview of prostate cancer occurrence using population-based incidence and mortality data from the National Cancer Institute and the Centers for Disease Control and Prevention. Prostate cancer incidence trends have reversed from a decline of 6.4% per year during 2007 through 2014 to an increase of 3.0% annually during 2014 through 2021. The increasing trend is confined to distant-stage disease in men younger than 55 years and to regional/distant-stage disease in men aged 55-69 years but includes early stage disease in men aged 70 years and older. Over the past decade of data, distant-stage disease has increased by 2.6% annually in men younger than 55 years, 6.0% annually in men aged 55-69 years, and 6.2% annually in men aged 70 years and older. American Indian/Alaska Native, Asian American/Pacific Islander, and Hispanic men are less likely than Black and White men to be diagnosed with localized disease (64%-67% vs. 71%-72%). Compared with White men, American Indian/Alaska Native men have 12% higher prostate cancer mortality despite 13% lower incidence, whereas Black men have double the prostate cancer mortality, with 67% higher incidence. In summary, continued increases in the diagnosis of advanced prostate cancer and persistent racial disparities underscore the need for redoubled efforts to optimize early detection while limiting overdiagnosis and to understand and address barriers to equitable outcomes.

Indexed as

Prostatic NeoplasmsAgedEarly Detection of CancerHumansIncidenceMaleMiddle AgedSEER ProgramUnited Statescancer screeningcancer statisticscancer surveillanceprostate cancerstage at diagnosis

Identifiers

PMID40892160
PMCPMC12593258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.