ReviewDermatologie (Heidelberg, Germany)2025
[Line-field confocal optical coherence tomography in keratinocyte cancer and margin delineation in basal cell carcinoma].
Review in Dermatologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
backgroundThe number of patients with keratinocyte tumors is steadily increasing. In addition, personnel and procedural costs for surgical treatment are also rising.
objectivesHow suitable are modern, noninvasive dermatological imaging devices for improving the efficiency of tumor diagnostics and therapy in keratinocyte skin cancer, thereby enhancing treatment outcomes? MATERIALS AND
methodsDescription of the process using a patient pathway and case studies, with discussion of existing literature and future perspectives. RESULTS AND DISCUSSION: Modern noninvasive imaging techniques such as line-field confocal optical coherence tomography (LC-OCT) offer promising approaches in the surgical treatment of keratinocyte skin cancer, enabling high-resolution real-time tumor diagnostics. Early studies show that LC-OCT can be used both for early diagnosis without biopsy and for preoperative margin delineation of basal cell carcinomas. These techniques allow for efficiency-enhancing concepts in modern tumor therapy. However, clinical data on the practicability of these methods are currently lacking, highlighting the urgent need for validated studies for critical evaluation.
conclusionNoninvasive imaging can increase the efficiency of diagnosis and treatment of keratinocyte tumors through early and rapid diagnosis as well as artificial intelligence-assisted surgical planning.
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