Evidence map›Paper›PMID 40892014›Full record

Observational studyCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025

Procedural Characteristics and Safety of Slender Percutaneous Coronary Intervention: Slender Is Better.

Fuminobu Yoshimachi, Kyohei Yamaji, Shun Kohsaka, Yota Kawamura, Satoshi Kasai, Toshiharu Fujii, Hirofumi Nagamatsu, Kazushige Amano, Yuka Karasawa, Shinichiro Yamada and 2 more

Abstract readObservational StudyComparative StudyMulticenter Study
In one paragraph

Observational study in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fuminobu YoshimachiDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.ORCID 0000-0003-3590-3376
Kyohei YamajiDepartment of Cardiovascular Medicine, Kyoto University School of Medicine, Kyoto, Japan.
Shun KohsakaDepartment of Cardiology, Keio University School of Medicine, Shinjuku, Japan.
Yota KawamuraDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.
Satoshi KasaiDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.
Toshiharu FujiiDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.
Hirofumi NagamatsuDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.
Kazushige AmanoDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.
Yuka KarasawaDepartment of Cardiology, Tokai University Hachioji Hospital, Hachioji, Japan.
Shinichiro YamadaDepartment of Cardiology, Kita-Harima Medical Center, Ono, Japan.
Yoshihisa NakagawaDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan.
Yuji IkariDepartment of Cardiology, Tokai University School of Medicine, Tokyo, Japan.

Funding

Kyohei Yakaji, MD, PhD, reports investigator-initiated grant funding from Abbott. Shun Kohsaka, MD, PhD, has received research funding from the Japan Society for the Promotion of Science and Pfizer and consulting fees from Novartis and Bristol Myers Squibb, outside of the submitted work. Yoshihisa Nakagawa, MD, PhD, has received research funding from Abbott Medical Japan. Yuji Ikari, MD, PhD, has received research funding from Boston Scientific, consulting fees from Nipro and Kaneka Medics, and royalties from Terumo.
6 · The paper itself

Abstract

objectivesWe aimed to examine the procedural characteristics and safety profile of slender percutaneous coronary interventions (PCI) using a 5 Fr or smaller sheath.

backgroundSmaller catheter size has been associated with fewer complications in PCI.

methodsOur retrospective observational study included 259,401 cases of stable elective PCI from the Japan Percutaneous Coronary Intervention Registry between 2021 and 2022. Based on sheath size, cases were categorized into the slender group (5 Fr or smaller, n = 28,300) and the non-slender group (6 Fr or larger, n = 231,101).

resultsThe slender group was associated with more radial access (88.6% vs. 74.2%: p < 0.001), fewer PCI failures (1.7% vs. 2.8%, p < 0.001), shorter procedural times (86.1 ± 47.2 min vs. 103.0 ± 65.1 min, p < 0.001), lower contrast medium usage (104.0 ± 54.8 mL vs. 126.0 ± 69.0 mL, p < 0.001), and shorter fluoroscopy times (25.9 ± 20.0 min vs. 32.4 ± 26.9 min, p < 0.001). Additionally, the slender group experienced fewer complications, including procedure-related myocardial infarction (odds ratio [OR] 1.25, p = 0.004), cardiac tamponade (OR 1.52, p = 0.048), heart failure or cardiogenic shock (OR 1.57, p < 0.001), stent thrombosis (OR 2.42, p = 0.02), emergency surgery (OR 3.45, p = 0.02), and bleeding complications at both the access (OR 3.16, p < 0.001) and non-access sites (OR 1.94, p = 0.02). Although the in-hospital mortality rate was slightly lower in the slender group, this difference was not statistically significant (OR 1.11, p = 0.39).

conclusionsSlender PCI using a 5 Fr or smaller sheath was associated with a favorable safety profile, shorter procedural times, and fewer complications compared to larger sheath sizes.

Indexed as

Cardiac CathetersCatheterization, PeripheralCoronary Artery DiseasePercutaneous Coronary InterventionAgedEquipment DesignFemaleHumansJapanMaleMiddle AgedPuncturesRegistriesRetrospective StudiesRisk AssessmentRisk Factorsbleeding complicationsminimally invasive coronary interventionpercutaneous coronary intervention complicationsradial artery accessslender intervention

Identifiers

PMID40892014
PMCPMC12584575

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.