ReviewRadiology2025
How I Do It: MRI of the Bone with Marrow-specific Sequences.
Review in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- [Differential diagnoses of malignant bone marrow diseases].Radiologie (Heidelberg, Germany) · 2026Review
- [Metabolism and bone marrow : Imaging of physiological and pathological processes].Radiologie (Heidelberg, Germany) · 2026Review
- Imaging of ewing sarcoma: an updated analysis including presenting features, prognostic imaging biomarkers, and treatment response assessment.Skeletal radiology · 2026Review
- Deep Learning-Augmented Zero Echo Time MRI Increases Diagnostic Confidence for Osseous Assessment in Hand and Foot MRI Protocols.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Normal bone marrow is composed of red marrow, which is hematopoietically active (producing red blood cells), and yellow marrow, which is hematopoietically inactive (composed mainly of fat cells). In infancy, bone marrow is mostly red marrow and converts to fatty yellow marrow in a systematic and predictable manner over time. Therefore, depending on the patient's age, the MRI appearance of normal bone marrow will change. In addition, red marrow reconversion from fatty yellow marrow wherein red replaces yellow bone marrow is a physiologic process that can occur due to stressors such as anemia, obesity, or chronic illness. Bone marrow conversion and reconversion are commonly encountered in routine practice, occasionally making the differentiation of normal from abnormal marrow challenging. True disorders of the bone marrow must be distinguished from normal marrow and include bone marrow replacement, infiltration, hyperemia-mediated reactive processes, ischemia with resultant necrosis, and bone marrow depletion. This review outlines a systematic approach to evaluating bone marrow at routine MRI, highlighting the role of clinically available noncontrast "marrow-specific" MRI sequences, which include T1-weighted spin-echo imaging, chemical shift imaging, and diffusion-weighted imaging with apparent diffusion coefficient mapping, for definitively characterizing the marrow signal for a focal or diffuse abnormality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.