Trial reportEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2025
Surgery Versus Surveillance: A Quality-of-Life Analysis of Patients With Moderately Dilated Aortic Root or Ascending Aorta.
Trial report in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Disease-specific emotional burden persists after surgical repair for thoracic aortic aneurysm.JTCVS open · 2026Article
Corrections and comments
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Authors and funding
27 authors.
Funding
Abstract
objectivesThe impact of diagnosis and management of ascending thoracic aortic aneurysm (ATAA) on patients' quality of life (QoL) is not well characterized. This study aims to compare QoL with surgery versus surveillance in patients with moderate ATAAs.
methodsTreatment In Thoracic Aortic aNeurysm: Surgery versus Surveillance is a multicentre randomized trial for patients with ATAA between 5.0 and 5.4 cm and includes a registry of patients who underwent either surgery or surveillance. From May 2019 to December 2022, 157 patients from 15 centres were enrolled in the surveillance (n = 105) or surgery (n = 52) registry and completed baseline and follow-up 36-item short form survey (SF-36) for QoL assessment. The primary outcomes were changes in physical component summary and mental component summary (MCS) scores. Propensity matching was performed to adjust for baseline differences.
resultsPatients in the surveillance arm were older and had higher prevalence of hypertension, dyslipidaemia, and atrial fibrillation (all P < 0.05). The overall mean duration between baseline and follow-up SF-36 questionnaire was 13.2 ± 3.6 months. After propensity match, compared to scores at baseline, patients in the surgery arm experienced significantly greater improvement in scores in MCS (4.1 ± 10.9 vs 0.1 ± 7.7; P = 0.04), general health (7.2 ± 17.6 vs -0.7 ± 14.5; P = 0.02), and mental health (9.5 ± 17.5 vs 1.4 ± 13.4; P = 0.01).
conclusionsIn a multicentre, prospective, non-randomized comparison of patients with moderate ATAAs, surgical treatment was associated with improvement in mental components of QoL at 1 year compared to surveillance.
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