Evidence map›Paper›PMID 40891852›Full record

ArticleMicrobiology spectrum2025

Evaluation of LLM-generated peptide as foundation template for discovery of effective encrypted AMPs against clinical superbugs.

Lanlan Zhao, Yihui Wang, Jun Jiang, Hongwei Pan, Lijuan Wang, Shutao Ma, Lei Zhang

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lanlan Zhao *Microbiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yihui Wang *Microbiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0001-6859-0375
Jun JiangDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine Shandong University, Jinan, China.
Hongwei PanDepartment of Clinical Laboratory, Qilu Hospital of Shandong University, Jinan, China.
Lijuan WangNeck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.ORCID 0000-0002-4463-3390
Shutao MaDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine Shandong University, Jinan, China.ORCID 0000-0003-1206-2375
Lei ZhangMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0003-4284-2604

Funding

National Natural Science Foundation of China 82172320, 82370785Shandong Provincial Natural Science Foundation ZR2024MH220Shandong University Outstanding Young Scholars Program
6 · The paper itself

Abstract

Novel antimicrobial agents are urgently needed to combat the antibiotic-resistance crisis, particularly in the face of multidrug-resistant (MDR) pathogens like carbapenem-resistant

Indexed as

Anti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesAcinetobacter baumanniiAnimalsBiofilmsDrug Resistance, Multiple, BacterialHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsReactive Oxygen SpeciesAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesReactive Oxygen Speciesantimicrobial peptidesCRABgenerative modelmultidrug-resistantsequence alignment

Identifiers

PMID40891852
PMCPMC12502564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.