Evidence map›Paper›PMID 40891820›Full record

ArticleMicrobiology spectrum2025

Identification of linear B-cell epitopes on the gE envelope protein of varicella-zoster virus.

Yan Niu, Jingming Zhou, Yankai Liu, Haili Wang, Hongliang Liu, Yumei Chen, Xifang Zhu, Chao Liang, Aiping Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan NiuSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.ORCID 0000-0001-9872-6800
Jingming ZhouSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Yankai LiuSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Haili WangLonghu Laboratory, Zhengzhou, Henan, China.
Hongliang LiuSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Yumei ChenSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Xifang ZhuSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Chao LiangSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Aiping WangSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.ORCID 0000-0003-1661-8174

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella-zoster virus (VZV) is a highly infectious DNA virus with an envelope. It is the pathogen causing varicella and herpes zoster. The glycoprotein E (gE) envelope protein, a primary target for VZV diagnostic reagents and vaccines, is highly immunogenic and plays a critical role in the pathogenicity of VZV. However, the B-cell epitopes and immunodominant regions of gE remain poorly characterized. In this study, we utilized anti-VZV gE monoclonal antibodies to localize antigenic sequences of gE at

Indexed as

Epitopes, B-LymphocyteHerpesvirus 3, HumanViral Envelope ProteinsAntibodies, MonoclonalAntibodies, ViralHerpes ZosterHumansAntibodies, MonoclonalAntibodies, ViralEpitopes, B-Lymphocyteglycoprotein E, varicella-zoster virusViral Envelope ProteinsB-cell epitopesgE envelope proteinvaricella-zoster virus

Identifiers

PMID40891820
PMCPMC12502664

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.