Evidence map›Paper›PMID 40891658›Full record

Observational studyOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Predictors of Decannulation Success in Tracheostomy: A 10-Year Analysis of the Global Tracheostomy Collaborative Database.

Charissa J Zaga, Carly E Milliren, Brendan A McGrath, Christina J Yang, Bradley A Schiff, Stephen J Warrillow, Jennifer K Henningfeld, Prudence A Gregson, Joshua R Bedwell, Karen M Beaudet and 2 more

Registry-linked trialAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07769021 (Observational iNternational Study of TRACHeostomy Practice in Adult Intensive Care Units - ON TRACH), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07769021 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Observational iNternational Study of TRACHeostomy Practice in Adult Intensive Care Units - ON TRACH

TypeobservationalSponsorRoyal College of Surgeons, IrelandRan2026 to 2029Enrolled2,500ConditionsTracheostomy Patients, Tracheostomy Decannulation, Intensive Care (ICU)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Redefining Nursing in Otorhinolaryngology-Head & Neck Care: Implications of the ICN's 2025 Definitions for an Evolving Specialty.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2026
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Charissa J ZagaDepartment of Speech Pathology, Division of Allied Health, Austin Health, Melbourne, Australia.
Carly E MillirenBiostatistics and Research Design Center, Boston Children's Hospital, Boston, Massachusetts, USA.
Brendan A McGrathNHS Foundation Trust, National Tracheostomy Safety Project, University of Manchester, Manchester, UK.
Christina J YangDepartment of Otorhinolaryngology-Head and Neck Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0002-2905-020X
Bradley A SchiffDepartment of Otorhinolaryngology-Head and Neck Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
Stephen J WarrillowDepartment of Critical Care, University of Melbourne, Melbourne, Australia.
Jennifer K HenningfeldTracheostomy and Home Ventilator Program, Division of Pulmonology, Department of Pediatrics, Children's Wisconsin, Milwaukee, Wisconsin, USA.
Prudence A GregsonThe Tracheostomy Review and Management Service, Austin Health, Melbourne, Australia.
Joshua R BedwellDepartment of Otolaryngology, Baylor College of Medicine, Houston, Texas, USA.
Karen M BeaudetPediatric Otolaryngology, Children's Mercy, Kansas City, Missouri, USA.
Michael J BrennerDepartment of Otolaryngology-Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-4926-0957
Vinciya PandianOtolaryngology-Head and Neck Surgery, College of Medicine, Hershey, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDecannulation is a critical milestone in functional recovery after tracheostomy, but standardized guidelines are lacking. This study examined factors associated with tracheostomy decannulation success, comparing hospital utilization, adverse events, and survival outcomes between decannulated and non-decannulated patients. STUDY

designRetrospective, observational study.

settingData were collected from 25 hospitals participating in the Global Tracheostomy Collaborative (GTC) in the United States, Australia, and the United Kingdom.

methodsProspectively collected data from adult patients who underwent tracheostomy from 2013 to 2022 were analyzed. Outcomes included decannulation success, hospital utilization metrics (intensive care unit [ICU] admissions, mechanical ventilation use, tracheostomy duration, and hospital length of stay), survival to discharge, discharge destinations, and adverse events. Associations were tested using t tests, chi-square, and Fine-Gray models, adjusting for clustering by site.

resultsAmong 5318 patients, 52.9% were decannulated before discharge. Predictors of decannulation included younger age, fewer comorbidities, elective and surgical admissions, and upper airway obstruction as an indication for tracheostomy versus facilitation of ventilation (all P < .001). Geographic variations were significant, with higher decannulation rates in Australia (82.1%) and the United Kingdom (70%) compared to the United States (13.5%) (P < .001). Decannulated patients had not only higher survival rates but also higher adverse events (11.4%, P = .002), particularly unplanned decannulation. Discharge destination varied by country, with the United Kingdom having the highest home discharge rate (P < .001).

conclusionDecannulation success is associated with patient and institutional factors, suggesting the need for standardized protocols to promote equitable tracheostomy management. Geographic variations in decannulation rates, adverse events, and hospital utilization suggest opportunities for harmonized guidelines to enhance outcomes and resource allocation.

Indexed as

Device RemovalTracheostomyAdultAgedAustraliaDatabases, FactualFemaleHumansLength of StayMaleMiddle AgedRespiration, ArtificialRetrospective StudiesTreatment OutcomeUnited KingdomUnited Statesadverse eventsairwayclinical outcomesclinical practice guidelinescritical caredecannulationhospital utilizationICU admissionintensive care unitlaryngotracheal injurylength of staymechanical ventilationmortalitymultidisciplinary carepatient‐centered carepatient safetyquality improvementquality of liferehabilitationreintubationrisk factorsspeechsubglottic stenosissurvivalsurvivorshipswallowingtracheostomytracheotomyventilatorventilatory support

Identifiers

PMID40891658
PMCPMC12574625

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.