Evidence map›Paper›PMID 40891593›Full record

ArticleNMR in biomedicine2025

Probing Intracellular Yeast Metabolism With Deuterium Magnetic Resonance Spectroscopy.

Fatima Anum, Charbel Assaf, Farhad Haj Mohamad, Maria Anikeeva, Arne Brahms, Jyotirmoy Dey, Simon Kaltenberger, Eric Beitz, Lina Welz, Victoria Annis and 4 more

Abstract read
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fatima AnumSection Biomedical Imaging, Molecular Imaging North Competence Center, Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0009-0007-2517-8867
Charbel AssafSection Biomedical Imaging, Molecular Imaging North Competence Center, Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0003-1968-2112
Farhad Haj MohamadSection Biomedical Imaging, Molecular Imaging North Competence Center, Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0009-0005-2238-5639
Maria AnikeevaSection Biomedical Imaging, Molecular Imaging North Competence Center, Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0002-2443-9910
Arne BrahmsOtto Diels Institute of Organic Chemistry, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0002-1788-6974
Jyotirmoy DeyOtto Diels Institute of Organic Chemistry, Kiel University, Kiel, Germany.ORCID https://orcid.org/0009-0003-8250-0753
Simon KaltenbergerOtto Diels Institute of Organic Chemistry, Kiel University, Kiel, Germany.ORCID https://orcid.org/0009-0001-7580-2732
Eric BeitzPharmaceutical Institute, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0001-5912-6626
Lina WelzInstitute of Clinical Molecular Biology, Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0009-0008-3779-623X
Victoria AnnisCentre for Hyperpolarization in Magnetic Resonance, University of York, York, UK.ORCID https://orcid.org/0009-0008-5062-9970
Manuel van GemmerenOtto Diels Institute of Organic Chemistry, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0003-3080-3579
Simon DuckettCentre for Hyperpolarization in Magnetic Resonance, University of York, York, UK.ORCID https://orcid.org/0000-0002-9788-6615
Jan-Bernd HövenerSection Biomedical Imaging, Molecular Imaging North Competence Center, Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0001-7255-7252
Andrey N PravdivtsevSection Biomedical Imaging, Molecular Imaging North Competence Center, Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0002-8763-617X

Funding

BMBF Hyperquant Consortium 03WIR6208A9DFG 469366436DFG 527469039DFG 555951950DFG BE-2253/8DFG EXC2167DFG FOR5042DFG HO-4602/3DFG TRR2879European Regional Development Fund (ERDF)European Union's Horizon 2020 946044German Federal Ministry of Education and Research (BMBF) 01ZX1915CMedical Faculty of Kiel UniversityStudienstiftung des deutschen VolkesZukunftsprogramm Wirtschaft of Schleswig-Holstein 122-09-053
6 · The paper itself

Abstract

Metabolomics provides snapshots of states of metabolites under specific conditions, with nuclear magnetic resonance (NMR) being one of the few noninvasive techniques. However, when applied to intact cells (e.g., yeast or mammalian cells) or tissues, traditional

Indexed as

DeuteriumIntracellular SpaceSaccharomyces cerevisiaeMagnetic Resonance SpectroscopyMetabolomicsDeuteriumdeuterium labelingDMRSintracellular metabolismmetabolomicsnoninvasiveosmotic stressreal‐time flux measurementSaccharomyces cerevisiae

Identifiers

PMID40891593
PMCPMC12403501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.