Evidence map›Paper›PMID 40891502›Full record

ArticleThe FEBS journal2026

Structural insights into how vacuolar sorting receptor recognizes the C-terminal sorting determinant of a vicilin-like seed storage protein.

Shu Nga Lui, Hsi-En Tsao, Anthony Hiu-Fung Lo, Liwen Jiang, Kam-Bo Wong

Abstract read
In one paragraph

Article in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shu Nga LuiCentre for Protein Science and Crystallography, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Hsi-En TsaoCentre for Protein Science and Crystallography, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Anthony Hiu-Fung LoCentre for Protein Science and Crystallography, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Liwen JiangCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-7829-1472
Kam-Bo WongCentre for Protein Science and Crystallography, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-6984-5373

Funding

Research Grants Council of Hong Kong 14118122Research Grants Council of Hong Kong 14151416Research Grants Council of Hong Kong AoE/M-05/12Research Grants Council of Hong Kong AoE/M403/16Research Grants Council of Hong Kong C2003-22WResearch Grants Council of Hong Kong C4012-16EResearch Grants Council of Hong Kong C4033-19EResearch Grants Council of Hong Kong C4041-18EF
6 · The paper itself

Abstract

During seed development, vacuolar sorting receptors (VSRs) recognize a sequence-specific vacuolar sorting determinant located at the C terminus (ctVSD) of storage proteins, thereby sorting them into protein storage vacuoles. The protease-associated (PA) domain of VSRs is responsible for interacting with the ctVSD of cargo proteins. Here, we report the crystal structure of the PA domain of Arabidopsis vacuolar-sorting receptor 1 (VSR1) in complex with the C-terminal pentapeptide (

Indexed as

ArabidopsisArabidopsis ProteinsPlant ProteinsSeed Storage ProteinsAmino Acid SequenceCrystallography, X-RayModels, MolecularProtein BindingProtein DomainsProtein TransportSeedsVacuolesArabidopsis ProteinsPlant ProteinsSeed Storage Proteinsvicilin protein, plantcrystal structureprotein–protein interactionreceptor‐mediated traffickingvacuolar sorting

Identifiers

PMID40891502
PMCPMC12796998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.