ArticleACS synthetic biology2025
Complex Kinetic Models Predict β-Carotene Production and Reveal Flux Limitations in Recombinant
Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Parallel gene amplification by Cas9 nickase for generating functionally heterogeneous cell populations.Cell reports methods · 2026Article
- Advances in the heterologous biosynthesis of QS saponins: a review.Microbial cell factories · 2026Review
- Strategies for Metabolic Engineering ofMolecules (Basel, Switzerland) · 2026Review
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2 authors.
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Abstract
β-Carotene is a high-value compound with multiple commercial applications as a pigment and due to its antioxidant properties. For its industrial production, precision fermentation using engineered microorganisms has been proposed as an attractive alternative given consumer concerns and technical limitations of traditional production methods such as chemical synthesis and extraction from plants. However, the factors limiting microbial production are complex and remain poorly understood, hindering bioprocess scale-up. To tackle this limitation, we built and evaluated kinetic model ensembles of the native mevalonate and the heterologous β-carotene production pathways in recombinant
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