ArticleJournal of the American Heart Association2025
Periprocedural Assessment of Coronary Microcirculatory Function to Predict Clinical Outcomes After Elective Percutaneous Coronary Intervention.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPercutaneous coronary intervention (PCI) could restore epicardial blood flow through the stent-based angioplasty. However, coronary microcirculatory function also affects clinical outcomes and can be quantified by the angiography-derived index of microcirculatory resistance (angio-IMR). The prognostic significance of periprocedural angio-IMR in patients undergoing elective PCI remains unclear. This study aimed to assess angio-IMR before and after PCI, as well as their association with long-term prognosis.
methodsData from 1768 patients with stable coronary artery disease undergoing elective PCI were analyzed. The primary end point was major adverse cardiac events (MACE) comprising death and nonfatal myocardial infarction.
resultsThe median angio-IMR was 11.3 (interquartile range, 7.7-15.0) and 17.0 (interquartile range, 14.1-20.4) before and after PCI (
conclusionsΔangio-IMR was a predictor of MACE in patients with stable coronary artery disease undergoing elective PCI. Incorporating Δangio-IMR could enhance the identification of patients at high risk of MACE.
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