SynthesisMovement disorders clinical practice2026
Movement Disorders in Neuromyelitis Optica Spectrum Disorder: A Systematic Review.
Synthesis in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Movement Disorders in MOGAD: A Systematic Review.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Opsoclonus-Myoclonus-Ataxia Revealing Underlying Neuromyelitis Optica Spectrum Disorder.Movement disorders clinical practice · 2026Article
- Patient education for neuromyelitis optica spectrum disorder using large language models: combining expert assessment and real-world patient interaction.Frontiers in physiology · 2026Article
- Pseudoathetotic Pseudodystonia as a Manifestation of Isolated Medullary Demyelination in Neuromyelitis Optica Spectrum Disorder.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral movement disorders (MD) have been reported to occur in neuromyelitis optica spectrum disorder (NMOSD). No extensive review has addressed the whole spectrum of MD in NMOSD.
objectiveThis article aims to review MD in NMOSD, describing its prevalence and features.
methodsA systematic review and prevalence meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. We included articles on NMOSD patients with MD as defined by the 2015 international consensus criteria. Meta-analysis was considered feasible if the prevalence of certain MDs was evaluated for at least 4 studies with more than 5 patients.
resultsNinety-six articles were selected from an initial pool of 5441, involving 1751 patients, of whom 487 had MD. The prevalence of anti-aquaporin-4 antibodies (AQP4-IgG) was 79.9% in general and 78.7% in NMOSD-MD patients. Tonic spasms/paroxysmal dystonia and ataxia were the most prevalent MD in NMOSD, with 39% and 26% prevalence, respectively. Tremor, parkinsonism, myoclonus, chorea, and other hyperkinetic disorders were more rarely reported.
conclusionsA wide range of MDs in NMOSD were found, each with distinct features and frequency in literature. This knowledge might help to identify patients with NMOSD, which presents MD as a clinical feature and improves outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.