Evidence map›Paper›PMID 40890685›Full record

ArticleBMC musculoskeletal disorders2025

Defining region and duration-specific substantial clinical benefit values for the simplified Chinese lower extremity functional scale.

Yongni Zhang, Yuan Gao, Dongmei Ai, Weimin Li, Xin Zhang, Xiongwei Xu, NanNan Zhang, Yixiong Yi, Haoyu Hu, Songbin Yang and 2 more

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Yongni ZhangDuquesne-China Health Institute, Duquesne University, Pittsburgh, PA, USA.
Yuan GaoDepartment of Rehabilitation Medicine, Zibo Traditional Chinese Medicine Hospital, Zibo, Shandong, China.
Dongmei AiDepartment of Rehabilitation Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.
Weimin LiDepartment of Rehabilitation Medicine, The Second Affiliated Hospital of Hainan Medical University, Hainan, China.
Xin ZhangShanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, China.
Xiongwei XuDepartment of Rehabilitation Center, Kunshan Rehabilitation Hospital, Kunshan, Jiangsu, China.
NanNan ZhangDepartment of Sport Therapy, Shaanxi Rehabilitation Hospital, Xian, Shaanxi, China.
Yixiong YiDepartment of Rehabilitation Center, Anxi County Hospital of Traditional Chinese Medicine, Quanzhou, Fujian, China.
Haoyu HuShanghai University of Sport, Shanghai, China.
Songbin YangDepartment of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
RobRoy L MartinDepartment of Physical Therapy, Duquesne University, Pittsburgh, PA, USA.
Xiaowen LianDepartment of Rehabilitation Assessment, Rehabilitation Hospital Affilated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China. lianxiaowen@fjtcm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA single substantial clinical benefit (SCB) value for the Simplified Chinese Lower Extremity Functional Scale (SC-LEFS) that can be applied to those with lower extremity musculoskeletal injuries is available. However, unique SCB values defined by specific body region and symptom duration may enhance the precision of the SC-LEFS in clinical assessments.

methodsThis study aim to determine unique SCB values for the SC-LEFS based on symptom duration and body region. Patients aged 18-50 years referred to physical therapy with a non-arthritic musculoskeletal injury to the knee or ankle/foot completed the SC-LEFS at initial assessment and 4-weeks follow-up. Demographic information and duration of symptoms was also obtained. Patients were grouped based on symptom duration (≤ 3 months or > 3 months). To determine the SCB change score, patients were classified into "improved" and "not improved" groups based on self-report after 4-weeks of physical therapy. SCB values were determined to best distinguish between the two groups. Receiver operator characteristic (ROC) curve analysis defined the sensitivity and specificity for these SCB values.

results313 patients with a mean age of 33.7 (SD 9.3) years were included in the knee region analysis and 354 patients with a mean age of 32.9 (SD 9.4) years in the ankle/foot region analysis. For those with knee injuries, SCB values of 9.5 and 5.5 were found for patients with symptom duration ≤ 3 months and symptom duration > 3 months, respectively. For those with ankle/foot injuries, SCB values 12.5 and 8.5 were found for patients with symptom duration ≤ 3 months and symptom duration > 3 months, respectively. The sensitivity and specificity for these SCB values ranged from 0.67 to 0.72 and from 0.66 to 0.68, respectively, with area under the cures (AUC) being between 0.67 and 0.72 (95% confidence intervals: 0.57-0.87).

conclusionThis study determined specific SCB values for the SC-LEFS after four weeks of physical therapy based on region of injury and symptom duration. These unique values may better allow clinicians to distinguish those "improved" from "not improved" in Chinese-speaking patients with non-arthritic musculoskeletal knee, ankle, or foot injuries.

trial registrationThis project was registered with the Chinese Clinical Trial Registry (ChiCTR2100052104) on 2021-10-17.

Indexed as

Ankle InjuriesDisability EvaluationFoot InjuriesKnee InjuriesLower ExtremityAdolescentAdultChinaEast Asian PeopleFemaleHumansMaleMiddle AgedPhysical Therapy ModalitiesReference ValuesTime FactorsLower extremity functional scalePatient reported outcome measurePsychometric propertiesSubstantial clinical benefit

Identifiers

PMID40890685
PMCPMC12403479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.