Evidence map›Paper›PMID 40890594›Full record

ArticleBMC immunology2025

The complex inflammatory indexes predict the prognostic risk for patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Ge Song, Yan Liu, Ying Zhang, Weichao Shan, Qiyu Sun, Yuewen Qi, Jingyi Liu, Lixian Sun

Abstract read
In one paragraph

Article in BMC immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ge SongDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Yan LiuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Ying ZhangDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Weichao ShanDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Qiyu SunHebei Key Laboratory of Panvascular Diseases, Chengde, 067000, China.
Yuewen QiHebei Key Laboratory of Panvascular Diseases, Chengde, 067000, China.
Jingyi LiuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Lixian SunDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China. lixiansun01@126.com.

Funding

Government funded clinical medicine talent training project ZF2023252
6 · The paper itself

Abstract

introductionAn accurate assessment of prognostic risk is widely recognized to be important in improving the survival of patients with acute coronary syndrome (ACS). This study aimed to investigate the roles of neutrophil-to-lymphocyte * platelet (NLPR) and neutrophil-lymphocyte (NLR) ratios with high- and (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels in predicting the risk of major adverse cardiovascular events (MACEs) in patients with ACS undergoing percutaneous coronary intervention (PCI).

resultsOverall, 1,263 patients with ACS undergoing PCI between January 2016 and December 2018 were consecutively enrolled. The patients were divided into MACEs (n = 54) and non-MACEs (n = 1,209) groups. The study endpoints were MACEs, including cardiac-related mortality and re-hospitalization for severe heart failure (HF), myocardial infarction (MI), and in-stent restenosis (ISR). The Kaplan-Meier curve showed the low NLPR and NLR groups had higher cumulative survival than the high NLPR and NLR group. Patients with high NLPR/HDL-C, NLPR×LDL-C, NLR/HDL-C, and NLR×LDL-C also had significantly lower cumulative survival.

conclusionNLPR ≥ 2.843, NLPR/HDL-C ≥ 1.977, NLPR*LDL-C ≥ 4.608, NLR ≥ 0.025, NLR/HDL-C ≥ 0.030, and NLR*LDL-C ≥ 0.038 were all independent prognostic risk factors in patients with ACS undergoing PCI, which may be useful markers for long prognosis.

Indexed as

Acute Coronary SyndromePercutaneous Coronary InterventionAgedBiomarkersBlood PlateletsCholesterol, HDLCholesterol, LDLFemaleHumansLymphocytesMaleMiddle AgedNeutrophilsRisk FactorsSurvival AnalysisBiomarkersCholesterol, HDLCholesterol, LDLAcute coronary syndromeNeutrophil-lymphocyte ratioNeutrophil-to-lymphocyte * platelet ratioPercutaneous coronary interventionPrognosis

Identifiers

PMID40890594
PMCPMC12400584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.