Article in The EMBO journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Lijun Chen *Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, 230032, Hefei, China.ORCID http://orcid.org/0009-0004-9931-4292
Chao Peng *Department of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, 230022, Hefei, China.ORCID http://orcid.org/0009-0008-5988-3270
Lanyi Chai *Department of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, 230022, Hefei, China.
Renjie Zhang *Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, 230032, Hefei, China.
Chenghang ZhuDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, 230022, Hefei, China.
Hailin WangDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, 230022, Hefei, China.
Qirong ChengDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, 230022, Hefei, China.
Cailiang ShenDepartment of Orthopedics, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, 230032, Hefei, China.
Hong ZhengDepartment of Pathophysiology, School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, 230022, Hefei, China.ORCID http://orcid.org/0000-0002-4048-6530
Jiazhao Yang *Department of Orthopedics, The First Affiliated Hospital of USTC, 17 Lujiang Road, 230001, Hefei, China. yangjiazhao@ustc.edu.cn.ORCID http://orcid.org/0000-0002-3473-7401
Haitao Fan *Department of Orthopedics, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, 315010, Ningbo, China. fyyfanhaitao@nbu.edu.cn.ORCID http://orcid.org/0009-0009-5436-2078
Chen Kan *Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, 230032, Hefei, China. chenkan@ahmu.edu.cn.ORCID http://orcid.org/0000-0003-1205-7410
Funding
Anhui Postdoctoral Science Foundation () 2025A1038Basic and Clinical Cooperative Research Incubation Project of Anhui Medical University for The Third Affiliated Hospital 2023sfy016China Postdoctoral Foundation Project | National Postdoctoral Program for Innovative Talents (Postdoctoral Innovation Talent Support Program of China) GZC20240010China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) 2024T026AHMOST | National Natural Science Foundation of China (NSFC) 82102573 and 82472531| Natural Science Foundation of Anhui Province () 2408085MH197NBST | Natural Science Foundation of Ningbo Municipality () (2024J031The Young Science and Technology Talent Lifting Program of Anhui Provincial Association for Science and Technology RCTJ202428| University Natural Science Research Project of Anhui Province () 2023AH053407
6 · The paper itself
Abstract
Tendon injury promotes aberrant osteochondral differentiation of tendon stem cells (TSCs) and results in disability. However, the cellular subsets within the osteochondral lineage involved in this process and associated mechanisms remain unclear. Here, we found that, following Achilles tenotomy, murine Gli1
Indexed as
Cell DifferentiationChondrogenesisChromograninsCyclic AMP-Dependent Protein KinasesGTP-Binding Protein alpha Subunits, GsOsteogenesisSignal TransductionStem CellsTendonsZinc Finger Protein GLI1Achilles TendonAnimalsHumansMiceChromograninsCyclic AMP-Dependent Protein KinasesGli1 protein, mouseGnas protein, mouseGTP-Binding Protein alpha Subunits, GsZinc Finger Protein GLI1Glioma-associated Oncogene Homolog 1 (Gli1)Guanine Nucleotide-Binding Protein (s) Alpha (Gnas)Heterotopic OssificationProtein Kinase A (PKA)Tendon Sheath Progenitors
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
GNAS/PKA signaling promotes aberrant osteochondral differentiation of Gli1 · full record | OpenQuestion