ArticleScientific reports2025
Maternal vitamin D intake correlates with serum 25-Hydroxyvitamin D, Interleukin-6, and ferritin in maternal and umbilical cord.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Dietary vitamin D intake and serum 25(OH)D concentrations in Minangkabau pregnant women: results from the vitamin D pregnant mothers (VDPM) cohort study in Indonesia.BMC pregnancy and childbirth · 2026Article
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5 authors.
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Abstract
Background Vitamin D is associated with fetal growth and development. It also plays an essential role in the body's immune system and placental regulation of the mother. This study investigated the correlation between vitamin D intake and 25-hydroxyvitamin D, interleukin-6, and ferritin levels in the maternal and umbilical cord. Materials and methods A cross-sectional study was conducted from June to December 2022 in Hermina Hospital, General Hospital Bunda Padang, and Army Hospital Dr. Reksodiwiryo. A total of 40 pregnant persons were observed in this study. The participants approved and signed the informed consent. The data were collected using a food frequency questionnaire. Maternal and umbilical cord serum were analyzed using enzyme-linked immunosorbent assay. All data were normally distributed, and the Pearson correlation test was performed. Results Mean vitamin D intake was 16,54 ± 2,92 mcg, maternal and umbilical cord serum 25(OH)D levels were 14,74 ± 4,93 ng/mL and 17,02 ± 5,94 ng/mL, maternal and umbilical cord serum IL-6 levels were 81,04 ± 12,23 and 98,75 ± 16,58 ng/L, maternal and umbilical cord serum ferritin levels were 41 ± 50,97 and 122,97 ± 71,23 ng/mL. There was a moderate correlation between vitamin D intake and serum 25(OH)D maternal (r = 0,379 and p = 0,016) and umbilical cord (r = 0,490 and p = 0,001). Vitamin D intake showed weak, non-significant correlations with maternal IL-6 (r = 0,292, p = 0,068) and umbilical cord IL-6 (r=-0,243, p = 0,131), and negligible correlation with maternal (r = 0,006, p = 0,971) and umbilical cord ferritin (r=-0,205, p = 0,204). Conclusions This study found a moderate correlation between maternal vitamin D intake and serum 25(OH)D, but weak correlations with IL-6 and ferritin.
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