Evidence map›Paper›PMID 40890316›Full record

ArticleScientific reports2025

Eco-friendly synthesis of silver nanoparticles using Anemone coronaria bulb extract and their potent anticancer and antibacterial activities.

Melek Yüce, Esra Albayrak, Arife Kübra Yontar, Sinem Çevik, Cagri Gumuskaptan

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melek YüceHealth Services Vocational School, Ondokuz Mayıs University, Samsun, Turkey. melek.yuce@omu.edu.tr.ORCID http://orcid.org/0000-0002-3791-838X
Esra AlbayrakStem Cell Research and Application Center, Ondokuz Mayıs University, Samsun, Turkey.ORCID http://orcid.org/0000-0002-9114-6253
Arife Kübra YontarDepartment of Mechanical and Metal Technologies, Ondokuz Mayis University, Samsun, Turkey.ORCID http://orcid.org/0000-0003-1486-9332
Sinem ÇevikDepartment of Metallurgical and Materials Engineering, Ondokuz Mayis University, Samsun, Turkey.ORCID http://orcid.org/0000-0002-3506-7892
Cagri GumuskaptanDepartment of Medical Biology, Faculty of Medicine, Hitit University, Çorum, Turkey.ORCID http://orcid.org/0000-0002-8600-172X

Funding

Ondokuz Mayis Üniversitesi PYO.KÖK.1908.23.001
6 · The paper itself

Abstract

Silver nanoparticles (AgNPs) have emerged as promising multifunctional agents in biomedical applications due to their notable antimicrobial and anticancer properties. In this study, we present a green, sustainable, and cost-effective method for synthesizing AgNPs using the bulb extract of Anemone coronaria, an underutilized plant part that allows year-round resource-efficient production. The synthesized AgNPs were characterized by UV-Visible spectroscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR). The nanoparticles exhibited a characteristic UV-Vis absorption peak at 425 nm, spherical morphology with an average size of 29 nm, and a face-centered cubic crystalline structure. FTIR analysis confirmed the presence of phytochemicals involved in the reduction and stabilization of AgNPs. The biosynthesized AgNPs showed potent antibacterial activity against both Gram-positive and Gram-negative bacteria, and demonstrated significant cytotoxic effects on cancer cells while sparing normal cells. Apoptosis induction, cell cycle arrest, and gene expression analyses further validated their anticancer efficacy. These findings highlight the therapeutic potential and biocompatibility of Anemone coronaria-derived AgNPs, offering a green nanotechnological approach for future biomedical applications.

Indexed as

AnemoneAnti-Bacterial AgentsAntineoplastic AgentsMetal NanoparticlesPlant ExtractsSilverApoptosisCell Line, TumorGreen Chemistry TechnologyHumansMicrobial Sensitivity TestsSpectroscopy, Fourier Transform InfraredX-Ray DiffractionAnti-Bacterial AgentsAntineoplastic AgentsPlant ExtractsSilverAnemone coronariaAntibacterialAnticancerBulb extractsEco-friendlySilver nanoparticles

Identifiers

PMID40890316
PMCPMC12402268

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.