Evidence map›Paper›PMID 40889948›Full record

Observational studyBMJ paediatrics open2025

Alterations in diaphragmatic activity preceding and during intermittent hypoxaemia events in preterm infants.

Ruud W van Leuteren, Lieke A P Arts, Fabio A Blom, Frans H de Jongh, Anton H van Kaam, G Jeroen Hutten

Abstract readObservational Study
In one paragraph

Observational study in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruud W van LeuterenDepartment of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands r.w.vanleuteren@amsterdamumc.nl.ORCID http://orcid.org/0000-0001-8468-2544
Lieke A P ArtsDepartment of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0006-0873-2101
Fabio A BlomDepartment of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Frans H de JonghDepartment of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Anton H van KaamDepartment of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
G Jeroen HuttenDepartment of Neonatology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the activity of the diaphragm using electromyography (dEMG) prior and during apnoea-induced intermittent hypoxaemia (IH) events in preterm infants

designA single-centre observational study.

settingNeonatal intensive care unit. PATIENTS: Preterm infants (<32 weeks of gestation) experiencing IH events with a frequency of >1/hour

methodsHeart rate, oxygen saturation (SpO

results20 infants (gestational age 27.6±1.3 weeks) were included. A total of 591 IH events were used for analysis of which 88 (14.9%), 239 (40.4%) and 264 (44.7%) were scored as central, obstructive and mixed, respectively. In the 1 min before the actual IH, dEMG

conclusiondEMG can detect and characterise central and obstructive apnoea before the IH event occurs, which supports development of automated detection and classification of apnoea events.

Indexed as

ApneaDiaphragmHypoxiaInfant, Premature, DiseasesElectromyographyFemaleGestational AgeHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleOxygen SaturationNeonatologyPhysiology

Identifiers

PMID40889948
PMCPMC12406875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.