SynthesisBrain and behavior2025
Efficacy and Safety of Neuroendoscopy versus Craniotomy for Spontaneous Supratentorial Intracerebral Hemorrhage: An Updated Meta-Analysis of Randomized and Non-Randomized Studies.
Synthesis in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Neuroendoscopy versus Craniotomy for Spontaneous Supratentorial Intracerebral Hemorrhage: An Updated Meta-Analysis of Randomized and Non-Randomized Studies.Brain and behavior · 2025Pooled it
- Comparing various surgical interventions versus conservative medical treatment in spontaneous supratentorial intracerebral hemorrhage: a network meta-analysis of the randomized controlled trials.Neurosurgical review · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundSpontaneous supratentorial intracerebral hemorrhage (ICH) is a critical condition with high morbidity and mortality rates warranting urgent surgical evacuation. This systematic review and meta-analysis compare the safety and efficacy of neuro-endoscopy (NE) versus traditional craniotomy (CR) for managing ICH.
methodsFrom inception until July 2024, a comprehensive literature search was undertaken on PubMed, Cochrane Central, ScienceDirect, and Clinicaltrials.gov. Risk ratios (RR) and weighted mean differences (WMD) were pooled for categorical and continuous outcomes under the random effects model in Review Manager software. 5.4.1. Leave-one-out sensitivity analysis, Egger's regression, GRADE assessment, and meta-regression were performed to evaluate the heterogeneity, publication bias, certainty of evidence, and effect size variability, respectively.
resultsOur meta-analysis included eight clinical trials and 20 cohort studies with 9,437 patients. NE outperformed CR in terms of favorable neurological outcomes (RR = 1.59, 95% CI: [1.30,1.94]; p < 0.00001; I
conclusionNE treatment for spontaneous intracerebral hemorrhage (ICH) is associated with favorable neurological outcomes, decreased mortality, shorter operating time, reduced blood loss and residual volume, shorter length of hospital and intensive care unit (ICU) stay, and fewer infections, meningitis, and overall complications; however, the re-bleeding rate was found to be comparable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.