ArticleGeroScience2026
Frailty, malnutrition risk, and kidney function impairment in older adults: Singapore longitudinal ageing study.
Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Kidney function declines progressively with age, with chronic kidney disease (CKD) affecting more than half of community-dwelling older adults. Identifying risk factors beyond the established ones (such as diabetes and hypertension) is crucial for prevention. Frailty and malnutrition are prevalent in older adults, yet the effect of these factors on their decline of kidney function remains underexplored. This study aimed to elucidate the associations between frailty, malnutrition, and renal function among community-dwelling older adults. In this prospective cohort study, we analysed the data of 2,292 Chinese older adults aged 55 and above from the Singapore Longitudinal Ageing Study. Frailty was assessed using the Cardiovascular Health Study criteria, and malnutrition risk was evaluated using the Nutritional Screening Initiative questionnaire. Kidney function was measured using estimated glomerular filtration rate (eGFR). Baseline and follow-up (3-5 years) associations between frailty, malnutrition, and kidney function, controlling for known confounding risk factors were examined. At baseline, malnutrition was associated with lower eGFR (β = -5.42; 95% CI -8.83--2.01) and higher CKD prevalence (OR = 2.24; 95% CI 1.13-4.46). The combined risk of frailty-malnutrition was also significantly associated with lower eGFR (β = -5.29; 95% CI -9.93--1.65) and CKD prevalence (OR = 3.05; 95% CI 1.22-7.60). At follow-up, malnutrition (aOR = 3.21; 95% CI 1.60-6.44) but not physical frailty (aOR = 0.70; 95% CI 0.19-2.55), was associated with significant kidney function decline. The results suggest that malnutrition plays a vital role in kidney function decline among community-dwelling older adults, more so than frailty. Integrating nutritional screening timely may optimise the long-term kidney health in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.